3-Oxotirucalla-7,24-dien-21-oic acid

3-Oxotirucalla-7,24-dien-21-oic acid
Product Name 3-Oxotirucalla-7,24-dien-21-oic acid
CAS No.: 82464-35-5
Catalog No.: CFN97609
Molecular Formula: C30H46O3
Molecular Weight: 454.69 g/mol
Purity: >=98%
Type of Compound: Triterpenoids
Physical Desc.: Powder
Source: The leaves of Rubus alceaefolius
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Price:
3-Oxotirucalla-7,24-dien-21-oic acid shows potent cytotoxicity against MCF-7 cell line.
Inquire / Order: manager@chemfaces.com
Technical Inquiries: service@chemfaces.com
Tel: +86-27-84237783
Fax: +86-27-84254680

Address:
1 Building, No. 83, CheCheng Rd., Wuhan Economic and Technological Development Zone, Wuhan, Hubei 430056, PRC
Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
  • Photodermatol Photoimmunol Photomed.2024, 40(1):e12950.
  • J Adv Res.2021, 35:245-257.
  • Nutrients.2023, 15(12):2644.
  • QASCF2022, 14(4).
  • In Vitro Cellular & Developmental Biology - Plant 2021, 57:874¨C882.
  • Nat Prod Commun.2018, 10.1177
  • Mol Cells.2018, 41(8):771-780
  • Universidade Estadual Paulista2017, 11449
  • Research Square2021, 10.21203.
  • Food Bioscience2024, 58:103691.
  • Pseudolarifuroic acid

    Catalog No: CFN91924
    CAS No: 130825-79-5
    Price: Inquiry(manager@chemfaces.com)
    3alpha-Hydroxytirucalla-7,24-dien-21-oic acid

    Catalog No: CFN95908
    CAS No: 82509-40-8
    Price: $318/5mg
    3-Oxotirucalla-7,24-dien-21-oic acid

    Catalog No: CFN97609
    CAS No: 82464-35-5
    Price: Inquiry(manager@chemfaces.com)
    Methyl kulonate

    Catalog No: CFN92975
    CAS No: 22611-37-6
    Price: Inquiry(manager@chemfaces.com)
    Parkeol

    Catalog No: CFN92825
    CAS No: 514-45-4
    Price: Inquiry(manager@chemfaces.com)
    Cucurbitadienol

    Catalog No: CFN92378
    CAS No: 35012-08-9
    Price: Inquiry(manager@chemfaces.com)
    Inotodiol

    Catalog No: CFN92367
    CAS No: 35963-37-2
    Price: $338/5mg
    3beta-Hydroxylanosta-8,24-diene-21-al

    Catalog No: CFN92365
    CAS No: 96574-03-7
    Price: $318/5mg
    Trametenolic acid

    Catalog No: CFN92366
    CAS No: 24160-36-9
    Price: $318/10mg
    Tsugaric acid A

    Catalog No: CFN90990
    CAS No: 174391-64-1
    Price: Inquiry(manager@chemfaces.com)
    Revista Brasileira de Farmacognosia.2014 Oct;24(5):561–564.
    Cytotoxic tirucallane triterpenes from the stem of Luvunga scandens.[Reference: WebLink]

    METHODS AND RESULTS:
    Two tirucallane triterpenes, namely flindissol (1) and 3-Oxotirucalla-7,24-dien-21-oic acid (2), were isolated from the dichloromethane extract of the stem of Luvunga scandens (Roxb.) Buch-Ham ex Wight & Arn, Rutaceae. This is the first report of their isolation from this plant. Their structures were constructed by high resolution mass and 2D NMR spectroscopic data. The cytotoxic potential of the two pure compounds 1 and 3-Oxotirucalla-7,24-dien-21-oic acid were determined by MTT assay against human breast adenocarcinoma cell line (MCF-7).
    CONCLUSIONS:
    Compounds 1 and 3-Oxotirucalla-7,24-dien-21-oic acid showed potent cytotoxicity against MCF-7 cell line with IC50 values of 13.8 μM and 27.5 μM, respectively. This result suggested their potential activity as antitumor agents.
    Zhong Yao Cai. 2015 Jan;38(1):93-6.
    Study on Chemical Constituents of Petroleum Ether Fraction from Rubus alceaefolius.[Pubmed: 26214876]
    To investigate the chemical constituents of Rubus alceaefolius.
    METHODS AND RESULTS:
    Nine compounds were isolated and purified from the petroleum ether extract of 95% alcohol extract of Rubus alceaefolius by repeated column chromatography on silica, Sephadex LH-20 and structurally identified by spectral analysis. The compounds were identified as chrysophanol(1), physcion (2), β-sitosterol(3), 3-oxotirucalla-7, 24-dien-21-oic acid(4), myricadiol(5), 19-α-hydroxy-3-acetyl-ursolic acid(6), N-benzoylphenylalaninyl-N-benzoylphenylalaninate(7), aurantiamide acetate(8) and euscaphic acid(9).
    CONCLUSIONS:
    Compounds land 4~8 are isolated from this plant for the first time, and compounds 4 - 8 are found in plants of Rubus genus for the first time.
    Alloisoimperatorin

    Catalog No: CFN95012
    CAS No: 35214-83-6
    Price: $338/5mg
    Naringin 4'-glucoside

    Catalog No: CFN95014
    CAS No: 17257-21-5
    Price: $338/5mg
    Momordicoside X

    Catalog No: CFN95170
    CAS No: 1333321-50-8
    Price: $368/5mg
    Astin A

    Catalog No: CFN95187
    CAS No: 151201-75-1
    Price: $318/10mg
    2-Methoxy-5-acetoxy-furanogermacr-1(10)-en-6-one

    Catalog No: CFN95197
    CAS No: 1809980-25-3
    Price: $318/10mg
    Quasipanaxatriol

    Catalog No: CFN95248
    CAS No: 171903-78-9
    Price: $413/5mg
    Vaccarin E

    Catalog No: CFN95252
    CAS No: 2252345-81-4
    Price: $318/10mg
    Ganolucidic acid B

    Catalog No: CFN95513
    CAS No: 98683-75-1
    Price: $413/5mg
    Methyl ganoderenate F

    Catalog No: CFN95573
    CAS No: N/A
    Price: $413/5mg
    Ephedrannin A

    Catalog No: CFN95579
    CAS No: 82001-39-6
    Price: $318/5mg