2',5,6',7-Tetrahydroxyflavanone
(2S)-2',5,6',7-Tetrahydroxyflavanone can inhibit the lipid peroxide formation induced by adenosine diphosphate and reduced nicotinamide adenine dinucleotide phosphate in rat liver homogenate.
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Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to
24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
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Chem Pharm Bull (Tokyo). 1982 May;30(5):1792-5.
Studies on scutellariae radix. VI. Effects of flavanone compounds on lipid peroxidation in rat liver.[Reference:
WebLink]
METHODS AND RESULTS:
Compounds (I and II) which inhibited lipid peroxides formation (in in vitro experiments) were isolated together with various flavonoids from the roots of Scutellaria baicalensis GEORGI. From the analytical and physical data, compounds I and II were identified as (2S)-2',5,6',7-Tetrahydroxyflavanone and (2R, 3R)-2', 3, 5, 6', 7-pentahydroxy-flavanone, respectively.
CONCLUSIONS:
Compound II inhibited the lipid peroxide formation by Fe2+ and ascorbic acid. Compounds I and II inhibited the lipid peroxide formation induced by adenosine diphosphate and reduced nicotinamide adenine dinucleotide phosphate in rat liver homogenate.
Yao Xue Xue Bao. 1989;24(3):200-6.
Studies on the structures of new flavonoids from the root of Scutellaria amoena.[Pubmed:
2816376 ]
METHODS AND RESULTS:
From the root of Scutellaria amoena C.H. Wright, two new flavonoids (I, II) and six known flavonoids (III-VIII) were isolated. On the basis of spectroscopic analysis (UV, 1HNMR, 13CNMR, MS and CD) and chemical evidences, the structures of I and II were elucidated as (2S)-2',5,6'-trihydroxy-7-methoxyflavanone-2'-O-beta-D-glucopyrano side (I) and (2R, 3R)-2',3,5,7-tetrahydroxyflavanone (II) respectively. The other six known compounds were identified as (2S)-5,7,8-trihydroxyflavanone (III), (2S)-2',5,6',7-Tetrahydroxyflavanone (IV), (2R, 3R)-2',3,5,6',7-pentahydroxyflavanone (V), 2',5,6',7-tetrahydroxyflavone (VI) norwogonin (VII) and oroxylin-A (VIII) respectively.
CONCLUSIONS:
Compounds III-VIII were obtained from this plant for the first time.
