2-2'-(Hydroxytetracosanoylamino)-octadecane-1,3,4-triol tetraacetate | CAS:340702-68-3

(2S,3S,4R,2′R )-2-(2′-Hydroxytetracosanoylamino) octadecane-1,3,4-triol at concentration of 100 ug/mL shows selectively inhibitory activity against phospholipase A 2 (PLA 2) secreted from Crotalus adamenteus venom, but inactive against PLA 2 of bee venom (Apis mellifcra).

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Chemical Constituents of the Fungus Leccinum extremiorientale[Reference: WebLink]

METHODS AND RESULTS:
Thirteen chemical constituents were isolated from the fruiting bodies of basidiomyctes Leccinum extremiorientale, and their structures were elucidated by spectral and physical-chemical data as: ergosta-7,22-dien-3β,5α,6β-triol (1), ergosterol peroxide (2), ergosterol (3), ergosta-4,6,8(14),22-tetraen-3-one (4), ergosta-5,7-dien-3β-ol (5), palmitic acid (6), (2S,3S,4R,2′R)-2-2'-(Hydroxytetracosanoylamino)-octadecane-1,3,4-triol (7), cerebroside B (8), cerebroside D (9), uracil (10), inosine (11), adeosine (12) and D-allitol (13). The NMR data of compounds 8 and 9 were completely assigned by 2D-NMR techniques, including 1H-1H COSY, HMBC and HMQC.
CONCLUSIONS:
Compounds 2, 7 and 8 at concentration of 100 μg/mL showed selectively inhibitory activity against phospholipase A 2 (PLA 2) secreted from Crotalus adamenteus venom, but inactive against PLA 2 of bee venom (Apis mellifcra). In addition, the methanol-chloroform soluble extract of this fungus also showed 67% antifeedant rate against Leucaninia separata and caused 55% mortality against Plutella xylostella after three-day application.

Product Name	2-2'-(Hydroxytetracosanoylamino)-octadecane-1,3,4-triol tetraacetate
CAS No.:	340702-68-3
Catalog No.:	CFN98439
Molecular Formula:	C₅₀H₉₃NO₉
Molecular Weight:	852.3 g/mol
Purity:	>=98%
Type of Compound:	Cerebrosides
Physical Desc.:	Powder
Source:	The herbs of Phyllanthus emblica
Solvent:	DMSO, Pyridine, Methanol, Ethanol, etc.
Price: