Polygonum multiflorum

Polygonum multiflorum is used in traditional Chinese medicine as a tonic and an anti-aging remedy. There is insufficient scientific evidence to determine its effectiveness for any treatment. Characterzation of polyphenolic compounds in the stems of P. multiflorum was conducted using HPLC, high resolution LC-MS and LC-MSn. Proanthocyanidins in particular were isolated in 4.8% yield using solvent extraction followed by Sephadex LH-20 fractionation. HPLC analysis using a diol column revealed oligomers (from dimer to nonamer) as minor components, with (epi)catechin monomeric units predominating, and oligomers with higher degree of polymerization being dominant. Thiolysis treatment of the proanthocyanidins using mercaptoacetic acid produced thioether derivatives of (epi)catechin as the major product and a mean value of the degree of polymerization of 32.6 was estimated from the ratio of terminal and extension units of the (epi)catechin. The isolated proanthocyanidins were shown to strongly inhibit α-amylase with an acarbose equivalence (AE) value of 1,954.7 µmol AE/g.

Research products of this plants
Emodin

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Chrysophanol

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Aloeemodin

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Physcion

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Rhein

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Resveratrol

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2,3,5,4'-Tetrahydroxyl diphenylethylene-2-O-glucoside

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Pinostilbenoside

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Gallic acid

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Catechin

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(-)-Epigallocatechin gallate

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Epicatechin

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(-)-Epigallocatechin(EGC)

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(-)-Gallocatechin gallate

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Emodin-8-beta-D-glucoside

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Tricin

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Daucosterol

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5,7-Dihydroxychromone

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