Hot Products

Azaleatin
Catalog No: CFN91007

Azaleatin is a natural product Rhododendron simsii.

Baccatin III
Catalog No: CFN98331

Baccatin III, which is the precursor for the semisynthesis of paclitaxel,exerts anti-tumor immunomodulatory activity in very low doses (0.05-0.5mg/kg),it reduces tumor progression by inhibiting the accumulation and suppressive function of MDSCs. Baccatin III also exerts immunomodulatory activities in vivo as well as in vitro on the MHC-restricted antigen presentation.

Bacopaside I
Catalog No: CFN93076

Bacopaside I is a modulator of Aquaporin-1 channel, has neuroprotective functions, it has anti-Alzheimer's disease, it ameliorates cognitive impairment in APP/PS1 mice via immune-mediated clearance of β-amyloid. Bacopaside I also exhibits an obvious antidepressant-like effect in mouse model of CUMS-induced depression that was mediated, at least in part, by modulating HPA hyperactivity and activating BDNF signaling pathway.

Bacopaside II
Catalog No: CFN93234

Bacopaside II is a potential anti-angiogenic agent, it can reduce endothelial cell migration and tubulogenesis and induce apoptosis. Bacopaside II shows antioxidant and antidepressant activities, it can inhibit both basal activity as well as verapamil-stimulated ATPase activity, suggesting its affinity towards P-gp.

Bacopaside IV
Catalog No: CFN91182

Reference standards.

Bacopaside N2
Catalog No: CFN91081

Reference standards.

Bacopaside V
Catalog No: CFN93267

Reference standards.

Bacopaside X
Catalog No: CFN91082

Bacopaside X (9.06 μM) showed binding affinity towards the D1 receptor.

Bacoside A
Catalog No: CFN91080

Bacoside A has a possible anticancer activity that could be inducing cell cycle arrest and apoptosis through Notch pathway in GBM in vitro. It exerts cytoprotective efficacy by attenuation of ROS generated through oxidative stress by an increase in the concentration of antioxidant enzymes and sustain membrane integrity which leads to restoring the damage caused by tBHP. Bacoside A can able to inhibit the progression of Experimental Autoimmune Encephalomyelitis (EAE) may be by the inhibition of inflammatory cytokines and chemokine evolved during active EAE. Bacoside A also has vasorelaxation.

Bacoside A3
Catalog No: CFN91088

Bacoside A3 has antioxidant potential, it shows comparatively higher neuroprotective response analysed as higher cell viability and decreased intracellular ROS. Bacoside A3 shows a newer potential role in the clinical management of opioid withdrawal induced depression. Bacoside A3 inhibited both basal activity as well as verapamil-stimulated ATPase activity, thus its affinity towards P-gp; the interaction of bacosides (A3/A) with Tryptophan hydroxylase (TPH) might up-regulate its activity to elevate the biosynthesis of 5-HT, thereby enhances learning and memory formation.