Hot Products

Astragaloside IV
Catalog No: CFN99171

Astragaloside IV can protect the myocardium against ischemia/reperfusion injury, inhibit adenovirus replication and apoptosis in A549 cells in vitro, has anti-fibrotic effect against systemic sclerosis, and may be useful in ameliorating food-induced metabolic syndrome and membranous nephropathy. It suppresses the activation of ERK1/2 and JNK, and downregulates matrix metalloproteases (MMP)-2, (MMP)-9 in MDA-MB-231 breast cancer cells.

Astragenol
Catalog No: CFN91686

Astragenol is an intermediate used for Astragenol derivative synthesis. Astragenol derivatives are promising anti-inflammatory agents for prostate cancer research.

Astrasieversianin VII
Catalog No: CFN90648

Isoastragaloside II is an astragaloside, which is isolated from the hairy root culture of Astragalus membranaceus.

Astringin
Catalog No: CFN92486

Astringinin is a potent antiarrhythmic agent with cardioprotective activity in ischemic and ischemic-reperfused rat heart, the beneficial effects of astringinin in the ischemic and ischemic-reperfused hearts may be correlated with its antioxidant activity and upregulation of NO production. Astringinin can significantly attenuate proinflammatory responses and hepatic injury after trauma-hemorrhage, the salutary effects of astringinin administration on attenuation of hepatic injury following trauma-hemorrhage are likely due to reduction of pro-inflammatory mediator levels.

Atractylenolide I
Catalog No: CFN99944

Atractylenolide I, a TLR4-antagonizing agent, shows a wide spectrum of pharmacological activities such as anti-inflammatory, digestion promoting,significant antitumor, and antioxidant effects. It ameliorates sepsis syndrome,liver and kidney functions by reduction of pro-inflammatory cytokines and LPS.

Atractylenolide II
Catalog No: CFN99945

Atractylenolide II has antiinflammatory activity, it can inhibit platelets activities and thrombus formation. Atractylenolide II has cytotoxic/apoptotic effects may via p38 activation ,ERK and Akt inactivation, p53 dependent, it also has antimelanoma effect by inhibiting STAT3 signalling.

Atractylenolide III
Catalog No: CFN99946

Atractylenolide III, a potential house dust mite control agent, has neuroprotection, gastroprotective, anti-cancer, and anti-inflammatory activities, it also may control immunological reactions by regulating the cellular functions of IL-6 in mast cells. It inhibited nuclear factor-κB and mitogen-activated protein kinase pathways in mouse macrophages, and inhibited Lipopolysaccharide-induced TNF- α and NO production in macrophages.

Atractylodin
Catalog No: CFN99535

Atractylodin has a good potential as a source for natural repellents, it could be developed as natural insecticide. Atractylodin has high lipase inhibitory activity with the IC50 of  39.12 μM.

Atractylone
Catalog No: CFN92066

Atractylone has inhibitory effects on mast cell-mediated allergic reactions, it regulates the degranulation of mast cell, proves its potential in the treatment of mast cell-mediated allergic reactions.

Atractyloside A
Catalog No: CFN98560

Atractyloside is a toxic compound from wedelia glauca. It acts as inhibitor of oxidative phosphorylation by a specific interference with energy-transfer reactions, the effect is due to inhibition of the ADP utilizing process in the coupling system. Atractyloside, has been proposed for the antibiotic oligomycin, is an inhibitor of the energy-transfer reactions in animal mitochondria; it inhibits the phosphate uptake and the respiratory stimulation induced by P1-acceptor, but it does not interfere with the so-called resting respiration.