Hot Products

Artesunate
Catalog No: CFN90313

Artesunate is a part of the artemisinin group of agents with an IC50 of < 5 μM for small cell lung carcinoma cell line H69. It is a potential inhibitor of STAT-3 and exhibits selective cytotoxicity of cancer cells over normal cells in vitro; A potent inhibitor of EXP1.Artesunate has anti-inflammatory activity, can prevent neuroinflammation in BV2 microglia by interfering with NF-κB and p38 MAPK signalling.

Artocarpesin
Catalog No: CFN91901

Artocarpesin has anti-inflammatory effects, it can suppress the LPS-induced production of nitric oxide (NO) and prostaglandin E 2 (PGE 2) through the down-regulation of inducible nitric oxide synthase (iNOS) and cyclooxygenase 2 (COX-2) protein expressions. Artocarpesin displays cytotoxic effects at various extent on all the 9 tested cancer cell lines with IC50 values respectively below 106 uM. Artocarpesin has interesting antimicrobial potency, and shows tyrosinase inhibitory activity.

Artocarpin
Catalog No: CFN97239

Artocarpin has anti- bactericidal effect, can reduce the viability of pneumococci by a factor of >1000, without obvious harm to lung epithelial cells. Artocarpin can prevent skin damage from UVB irradiation-induced photodamage in hairless mice and this is likely mediated through its antioxidant and anti-inflammation mechanisms.Artocarpin possesses potent 5alpha reductase inhibitory effect, it induces apoptosis in HSC-1 and T47D cells through modulation of MAPK and Akt/mTOR pathways, an extrinsic pathway, respectively. Artocarpin has an efficient lightening effect on UV-stimulated hyperpigmented dorsal skins of brownish guinea pigs.

ar-Turmerone
Catalog No: CFN89231

ar-Turmerone could be used as a low cost botanical insecticide for integrated management of cabbage looper in vegetable production. ar-Turmerone also shows larvicidal and biting deterrent activity against Aedes aegypti and Anopheles quadrimaculatus (Culicidae: Diptera). ar-Turmerone may have notable antibacterial activity to Bacillus cereus and Staphylococcus aureus, antifungal activity to Aspergillus niger, and cytotoxic activity to Hs 578T (breast tumor) and PC-3 (prostate tumor) cells. ar-Turmerone displays neuroprotective, and anticonvulsant properties, it exerts potent anti-inflammatory effects via suppression of the inflammatory cytokines IFN-γ and IL-2.

Arvenin III
Catalog No: CFN95327

Asarinin
Catalog No: CFN90628

Asarinin, a mammalian lignan precursor, has immunosuppression activity and can inhibit acute rejection in vitro. Asarinin may have a role on TLR4 pathway and produce prolongation of allograft heart survival. Asarinin induces dopamine biosynthesis via activation of the PKA-CREB-TH system and protects against 6-OHDA-induced cytotoxicity by inhibiting the sustained activation of the ERK-p38MAPK-JNK1/2-caspase-3 system in PC12 cells.

Asatone
Catalog No: CFN89486

Asatone has antifeedant activity.

Ascorbic acid
Catalog No: CFN90048

Ascorbic acid (Vitamin C) is a water-soluble vitamin indicated for the prevention and treatment of scurvy, it has a protective effect on alloxan-induced damage by maintaining the activity of cellular antioxidants, it also protects sperm from endogenous oxidative DNA damage that could affect sperm quality and increases risk of genetic defects, particularly in populations with low ascorbic acid such as smokers.Ascorbic acid can reverse endothelial vasomotor dysfunction in the brachial circulation of patients with coronary artery disease.

Asebogenin
Catalog No: CFN96928

Asebogenin has anti-bacterial activity, it shows inhibitory activity against S. aureus and methicillin-resistant S. aureus (IC50 of 10 and 4.5 micrograms/ml, respectively); it shows antiplasmodial activities against both a chloroquine-sensitive and a resistant strain of Plasmodium falciparum. Asebogenin can inhibit the proliferation of murine B cells.

Asebotin
Catalog No: CFN96929

Asebotin shows anti-influenza A virus activity, it also possesses potent antiviral activity (100% inhibition at the concentration of 1 ug /mL) against highly pathogenic avian influenza strain H5N1. Asebotin can inhibit the proliferation of murine B cells.