Hot Products

Tannic acid
Catalog No: CFN90501

Tannic acid has potential in the prevention of obesity.Tannic acid modifies silver nanoparticles are good candidates for microbicides used in treatment of herpesvirus infections.Tannic acid is directly harmful to larvae in a dose- and time-dependent manner and modulates immune responses of sheep WBC stimulated by H. contortus antigen by inhibiting Th1 cytokines and increasing Th2 cytokine expression in vitro.

Tanshindiol A
Catalog No: CFN92145

Reference standards.

Tanshindiol B
Catalog No: CFN92146

Tanshindiol B possesses a unique anti-cancer activity whose mechanism involves the inhibition of EZH2 activity and would provide chemically valuable information for designing a new class of potent EZH2 inhibitors. It also possesses the anti-angiogenic activity,so it can be a promising candidate for angiogenesis inhibitors.

Tanshindiol C
Catalog No: CFN92147

Tanshindiol C protects macrophages from oxLDL induced foam cell formation via activation of Prdx1/ABCA1 signaling and that Prdx1 may be a novel target for therapeutic intervention of atherosclerosis.It possesses a unique anti-cancer activity whose mechanism involves the inhibition of EZH2 activity and would provide chemically valuable information for designing a new class of potent EZH2 inhibitors.

Tanshinlactone
Catalog No: CFN99072

Standard reference

Tanshinol B
Catalog No: CFN90370

Reference standards.

Tanshinone I
Catalog No: CFN98953

Tanshinone I is an inhibitor of type IIA human recombinant sPLA2 (IC50=11 μM) and rabbit recombinant cPLA2 (IC50=82 μM). Tanshinone I possesses hepatocyte protective, anticancer, neuroprotection, and nephroprotective properties. Tanshinone I pretreatment causes significant suppression of skin cell death induces by solar simulated UV and riboflavin-sensitized UVA.

Tanshinone IIA
Catalog No: CFN98952

Tanshinone IIA is an estrogen receptor partial agonist with antiandrogenic properties, it has neuroprotective effects against cerebral ischemia/reperfusion injury and traumatic injury of the spinal cord in rats. Tanshinone IIA has anti-leukemia, anti-inflammatory and anti-oxidative properties, inhibits the release of inflammatory cytokines, such as, IL-1 β, IL-6 α, TNF-α.

Tanshinone IIA-sulfonic sodium
Catalog No: CFN90399

Tanshinone IIA sulfonate (sodium) is a water-soluble derivative of tanshinone IIA, which acts as an inhibitor of store-operated Ca2+ entry (SOCE), and is used to treat cardiovascular disorders.Sodium tanshinone IIA sulfonate pretreatment reduces infarct size and improves cardiac function in an ischemia-reperfusion-induced rat myocardial injury model via activation of Akt/FOXO3A/Bim-mediated signal pathway.

Tanshinone IIB
Catalog No: CFN99820

Co-treatment with Tanshinone IIB (TSB) significantly inhibits the DNA laddering, cytotoxicity and apoptosis of rat cortical neurons induced by staurosporine in a concentration-dependent manner; TSB also suppresses the elevated Bax protein and decreased bcl-2 and caspase-3 proteins induced by staurosporine in rat cortical neurons; TSB is effective in reducing stroke-induced brain damage and may represent a novel drug candidate for further development. TSB significantly inhibits the uptake of digoxin and vinblastine in membrane vesicles containing PgP or MRP1, moderately stimulates PgP ATPase activity, suggesting TSB is a substrate for PgP and MRP1 and that drug resistance to TSB therapy and drug interactions may occur through PgP and MRP1 modulation.