Hot Products

Streptozotocin
Catalog No: CFN93213

Streptozotocin, which produces diabetes mellitus in experimental animals, has been reported to reduce the level of NAD in pancreatic isletsand to inhibit islet synthesis of proinsulin.Streptozotocin can induce pancreatic insulitis, which is a new model of diabetes mellitus.

Strictosamide
Catalog No: CFN98237

Strictosamide possesses antibacterial and antiviral activities, it also may have important effects on inflammation and inflammatory pain. Strictosamide is slightly toxic to Charles River mouse (LD(50)=723.17 mg/kg), producing CNS depression and kidney toxicity. Strictosamide has nonsignificant in vitro and in vivo effect on kidney Na(+),K(+)-ATPase activity but produced an in vivo increase of Na(+),K(+)-ATPase activity of brain.

Strictosidine
Catalog No: CFN90499

Strictosidine has DNA damaging activity in yeast RS 188N mutant, assessed as drug level required to produce 12 mm zone of inhibition.

Strictosidinic acid
Catalog No: CFN96657

Strictosidinic acid has an antiradical action against DPPH, it has a promising effect in the central nervous system.

Strychnine
Catalog No: CFN98130

Strychnine-insensitive glycine site NMDA antagonist ( R )-HA-966 have neuroprotective effects in an experimental model of Parkinson's disease. Strychnine insensitive glycine receptor has anticonvulsant properties.Strychnine can block binaural inhibition in lateral superior olivary neurons, decrease the voltage-dependent Ca2+ current of both Aplysia and frog ganglion neurons. Strychnine also has inhibitory effects on GABA- and glycine-induced responses.

Stylopine
Catalog No: CFN92812

Stylopine can serve as a model compound for the design and future development of structurally related AKR1C3 inhibitors. It suppresses the NO and PGE2 production in macrophages by inhibiting the iNOS and COX-2 expressions, may contribute to the anti-inflammatory activity of Chelidonium majus.

Subelliptenone G
Catalog No: CFN99684

Subelliptenone G is a natural product from Garcinia hanburyi Hook.f.

Suberosin
Catalog No: CFN98985

Suberosin exhibits anti-inflammatory, and anticoagulant activities, it also shows biting deterrent activity against Aedes aegypti, it may be useful for use as mosquito larvicidal agent. Suberosin inhibits PHA-induced PBMC proliferation, at least in part, through reduction of [Ca2+]i, ERK, NF-AT, and NF-kappaB activation, and early gene expression in PBMC including cyclins and cytokines, and arrest of cell cycle progression in the cells.

Succinic acid
Catalog No: CFN99100

Succinic acid is a crystalline organic acid which occurs in living tissue as an intermediate in glucose metabolism.

Suchilactone
Catalog No: CFN95010

Suchilactone may have the potential to be developed as a treatment of Alzheimer's Disease.