Strictosidinic acid
Strictosidinic acid has an antiradical action against DPPH, it has a promising effect in the central nervous system.
Inquire / Order:
manager@chemfaces.com
Technical Inquiries:
service@chemfaces.com
Tel:
+86-27-84237783
Fax:
+86-27-84254680
Address:
1 Building, No. 83, CheCheng Rd., Wuhan Economic and Technological Development Zone, Wuhan, Hubei 430056, PRC
Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to
24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
Applied Biological Chemistry2024, 67:66.
Vojnosanit Pregl2016, 75(00):391-391
Antioxidants (Basel).2020, 9(6):526.
Front Pharmacol. 2024, 15:1527494.
Foods.2023, 12(19):3647.
Molecules.2020, 25(9):2081.
Food Bioscience2023, 59:103903
J Korean Society of Food Science & Nutrition2021, 50(9): 962-970
Applied Biological Chemistry2023, 66(58):112.
Vet World.2023, 16(3):618-630.
Related and Featured Products
Pharmaceutical Biology, 2008, 41(8):592-597.
Anti-allergic and Antioxidative Activities of Some Compounds from Thai Medicinal Plants.[Reference:
WebLink]
METHODS AND RESULTS:
In a DPPH radical scavenging assay, Strictosidinic acid and barakol were more potent than the positive control, BHT. The EC50 values of Strictosidinic acid and barakol were 27.68 and 39.62 μM, respectively. Other tested compounds, including lawsone methyl ether, bergenin, homorapanone and lucidin-ω-methyl ether, had weak antioxidative activities or no activity. In a nitrite assay, only lawsone methyl ether reduced nitrite production with an EC50 of 10.27 μM in RAW 264.7 cells.
CONCLUSIONS:
In conclusion, lawsone methyl ether suppresses degranulation in RBL-2H3 cells and reduces nitrite production in RAW 264.7 cells whereas Strictosidinic acid and barakol have an antiradical action against DPPH.
Phytomedicine. 2010 Mar;17(3-4):289-91.
Monoamine levels in rat striatum after acute intraperitoneal injection of strictosidinic acid isolated from Psychotria myriantha Mull. Arg. (Rubiaceae).[Pubmed:
19576739]
METHODS AND RESULTS:
Strictosidinic acid 10mg/kg, isolated from Psychotria myriantha leaves, were administered intraperitoneally to Wistar male rats (n=5-6). After 60 minutes, striatum was dissected, homogenized and injected onto HPLC-ED chromatographic system. It was observed a 28.7% reduction in the 5-HT levels followed up by an increase of 5-HIAA levels (29.4%). Furthermore there was a decrease of 8.0% in DA levels and an increase in the levels of metabolites DOPAC (21.5%) and HVA (52.5%).
CONCLUSIONS:
The results indicate that Strictosidinic acid has a promising effect in the central nervous system, justifying more studies about the central actions of Psychotria compounds.
5,7,2',4'-Tetrahydroxy-8,3'-di(gamma,gamma-dimethylallyl)-isoflavanone
Catalog No: CFN95084
CAS No: 141846-47-1
Price: $413/5mg
Methyl caffeate acid
Catalog No: CFN95561
CAS No: 3843-74-1
Price: Inquiry(manager@chemfaces.com)
(1E)-3-methoxy-8,12-epoxygermacra-1,7,10,11-tetraen-6-one
Catalog No: CFN95219
CAS No: 1393342-06-7
Price: $413/5mg
Vanillic acid glucoside
Catalog No: CFN95257
CAS No: 32142-31-7
Price: $368/10mg
8-Hydroxypinoresinol-4'-O-beta-D-glucopyranoside
Catalog No: CFN95356
CAS No: 102582-69-4
Price: $318/5mg
4-O-Coumaroylquinic acid
Catalog No: CFN95508
CAS No: 53539-37-0
Price: $318/5mg
2-(2,4-Dihydroxyphenyl)-5,6-methylenedioxybenzofuran (ABF)
Catalog No: CFN95511
CAS No: 67121-26-0
Price: $318/5mg
Hosenkoside D
Catalog No: CFN95521
CAS No: 156823-94-8
Price: $318/5mg
3''-O-Caffeoylhesperidin
Catalog No: CFN95564
CAS No: N/A
Price: $318/5mg
Ganosinensic acid C
Catalog No: CFN95567
CAS No: 2231756-23-1
Price: $413/5mg
