Hot Products

Testosterone
Catalog No: CFN90034

Testosterone prevents pancreatic β-cell apoptosis due to glucotoxicity through reduction of the expression of ATGR1 and its signaling pathway.Testosterone replacement therapy reduces insulin resistance and improves glycaemic control in hypogonadal men with type 2 diabetes. Testosterone can inhibit adipocyte differentiation in vitro through an AR-mediated nuclear translocation of beta-catenin and activation of downstream Wnt signaling.Testosterone inhibits estrogen-induced mammary epithelial proliferation and suppresses estrogen receptor expression.

Tetraethoxypropane
Catalog No: CFN90064

1,1,3,3-Tetraethoxypropane,the precursor of the ubiquitous natural compound malondialdehyde. Tetraethoxypropane as the standard in the thiobarbituric acid (TBA) assay.

Tetrahydro tanshinone I
Catalog No: CFN90460

Tetrahydro tanshinone I is one compound of Fufang Danshen Prescription (FDP) , liposome equilibrium dialysis system could simply and effectively esti-mate the absorption of multiple components in FDP in vivo, and predicts the potential bioactivity of these components, and thus contributes to the investigation of bioactive compounds with curative effect in FDP.

Tetrahydroalstonine
Catalog No: CFN97109

Tetrahydroalstonine and Raubasine preferentially block the pressor responses of post-synaptic alpha-adrenergic receptor activation due to exogenous and endogenouse noradrenaline, respectively.

Tetrahydroamentoflavone
Catalog No: CFN98755

Tetrahydroamentoflavone is a potent XO inhibitor, may be considered as a drug candidate or chemopreventive agent; it has anti-inflammatory effects, it shows in vitro cyclooxygenase (COX) inhibition activity ( an IC(50) value of 29.5 microM (COX-1) and 40.5% inhibition at 100 microg/mL (COX-2)). (2S,2″S )-Tetrahydroamentoflavone exerts its antioxidant activity in vitro through metal-chelating, and radical-scavenging, which is via donating a hydrogen atom (H61) and an electron (e).

Tetrahydroberberine
Catalog No: CFN90506

Tetrahydroberberine, with D(2) receptor antagonist and 5-HT(1A) receptor agonist properties, has significant potential as a therapeutic for treatment of FD; it has antidopaminergic effect, and other pharmacological action on the central nervous system. Tetrahydroberberine can inhibit the rabbit platelet aggregation.

Tetrahydrocannabivarin
Catalog No: CFN96627

Tetrahydrocannabivarin is a neutral cannabis receptor subtype (CB1) receptor antagonist, it can increases neural responding to rewarding and aversive stimuli, this effect profile suggests therapeutic activity in obesity, perhaps with a lowered risk of depressive side effects. Tetrahydrocannabivarin exhibits anticonvulsant effects in a piriform cortical brain slice model of epileptiform activity.

Tetrahydrocoptisine
Catalog No: CFN90416

Tetrahydrocoptisine is an active anti-inflammatory constituent by inhibition of TNF-α, IL-6 and NO production possibly via down-regulation of NF-κB activation, phospho-ERK1/2 and phospho-p38MAPK signal pathways.Tetrahydrocoptisine has gastroprotective activity, is attributed to reducing NO production and adjusting the pro-inflammatory cytokine, inhibited neutrophil accumulation and NF-κB expression.

Tetrahydrocurcumin
Catalog No: CFN90583

Tetrahydrocurcumin can inhibit tumor angiogenesis, treat human breast cancer,and be a promising candidate for the prevention of CIPN by chemotherapeutic agents.Tetrahydrocurcumin exhibits protective effects against cisplatin-induced oxidative renal damage in rats by inhibiting cyclooxygenase-2 and caspase-3 activation; it has a protective effect over arsenic induced toxicity in rat.

Tetrahydroepiberberine
Catalog No: CFN90507

Tetrahydroepiberberine is a natural product from Sinomenium acutum.