Hot Products

Rotenone
Catalog No: CFN98590

Rotenone is a mitochondrial complex I inhibitor that produces an animal model of Parkinson's disease. Rotenone-induced α-synuclein aggregation is mediated by the calcium/GSK3β signaling pathway. Rotenone can increase intracellular levels of the toxic dopamine metabolite 3,4-dihydroxyphenyl-acetaldehyde (DOPAL), via decreasing DOPAL metabolism by aldehyde dehydrogenase (ALDH) and decreasing vesicular sequestration of cytoplasmic dopamine by the vesicular monoamine transporter (VMAT).

Rotundine
Catalog No: CFN99195

Rotundine provides remarkable protection against cerebral ischemia reperfusion damage, its mechanisms may be through its influence on NO、ET 1 and energy metabolism. Rotundine injection can ameliorate the damages by modulating the activities of different types of NOS. It combined with methadone treatment may be a better therapeutic method in treatment of heroin dependence.

Roxadustat (FG-4592)
Catalog No: CFN60208

Royleanone
Catalog No: CFN96006

Royleanone possesses cytotoxic activity against the human pancreatic cancer cell line MIA PaCa-2.

Rubiadin
Catalog No: CFN99270

Rubiadin has hepatoprotective, antioxidant, and antitumor promoting effects. Rubiadin can decrease bone loss through the inhibition of osteoclast formation,differentiation and bone resorption.

Rubiadin 1-methyl ether
Catalog No: CFN97227

Rubiadin-1-methyl ether probed as Type I photosensitizers. Rubiadin 1-methyl ether decreases the number of parasites (schizonts) in a dose-dependent manner, and 100% of inhibition was obtained with 30 to 40 micrograms. Rubiadin-1-methyl ether shows strong enhancing activity for adipocyte differentiation, it could be beneficial in the treatment of diabetes. Rubiadin-1-methyl ether has therapeutic potential against osteoporosis, it can promote osteoblast proliferation and inhibit osteoclast TRAP activity and bone resorption, and the inhibitory effects on osteoclastic bone, antiosteoporotic activity of M. officinalis .

Rubiarbonol B
Catalog No: CFN99393

Rubiarbonol B may have antiplatelet aggregation activities.

Rubinaphthin A
Catalog No: CFN92603

Rubinaphthin A is a natural product from Rubia cordifolia.

Rubrisandrin A
Catalog No: CFN92278

Rubrisandrin A is an anti-HIV agent.

Rubrofusarin-6-O-beta-D-gentiobioside
Catalog No: CFN90827

Rubrofusarin-6-O-beta-D-gentiobioside can significantly decrease the expression of TGF-beta1 and fibronectin and NF-kappaB DNA binding activity, suggests that it has potential as a preventive agent for advanced glycation end products-related diabetic complications.