Hot Products

Isovitexin-2''-O-rhamnoside (2''-O-alpha-L-Rhamnopyranosyl-isovitexin)
Catalog No: CFN95314

Isovitexin 2′′-O-rhamnoside, a phenolic, has antioxidant and antiproliferative activities.

Isowighteone
Catalog No: CFN97166

Isowighteone, a compound that is not naturally produced in this species, accumulated by medicago truncatula hairy roots expressing LaPT1, indicates a strategy for metabolic engineering of novel antimicrobial compounds in legumes; it may have antimicrobial activity against fungal pathogens of plants.

Isoxanthohumol
Catalog No: CFN90768

Isoxanthohumol is a polyphenol with antioxidant, anti-inflammatory, and antiangiogenic properties, seems to regulate in vivo vascular proliferation and stabilization and the EC-VSMC-inflammatory crosstalk. Isoxanthohumol shows an antiviral activity towards herpes viruses (HSV1 and HSV2) and bovine viral diarrhea virus (BVDV).

Itraconazole
Catalog No: CFN60376

Ivacaftor (VX-770)
Catalog No: CFN60053

Ivacaftor (VX-770) is a selective potentiator of CFTR targeting G551D-CFTR and F508del-CFTR with EC50 of 100 nM and 25 nM in fisher rat thyroid cells, respectively.

Ivangustin
Catalog No: CFN92599

Ivangustin exhibits remarkable cytotoxicity against HEp2, SGC-7901 and HCT116 human cancer cell lines.

Izalpinine
Catalog No: CFN92777

Izalpinin exhibits potent antioxidant activities in the 1,1-diphenyl-2-picrylhydrazyl (DPPH) assay. Izalpinin exhibits inhibitory role of muscarinic receptor-related detrusor contractile activity, and it may be a promising lead compound to treat overactive bladder.

Jaceidin
Catalog No: CFN99032

Jaceidin demonstrates modest antioxidant activity, in a dose-dependent manner.

Jaceidin triacetate
Catalog No: CFN99482

Reference standards.

Jaceosidin
Catalog No: CFN90386

Jaceosidin has immunosuppressive, anti-oxidative, anti-inflammatory, and anticancer activities, it is also a microglial inhibitor with anti-neuroinflammation activity. Jaceosidin modulates the ERK/ATM/Chk1/2 pathway, leading to inactivation of the Cdc2-cyclin B1 complex, followed by G2/M cell cycle arrest in endometrial cancer cells. Jaceosidin inhibits T cell proliferation and activation, which is closely associated with its potent down-regulation of the IFN-γ/STAT1/T-bet signaling pathway.