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Isoscutellarein
Catalog No: CFN91491
8-Hydroxyapigenin (Isoscutellarein) is a brassinaceous compound derived from the plant Scutellaria baicalensis with anti-inflammatory, antioxidant and anti-influenza virus activity.
Isosilybin
Catalog No: CFN90260
Isosilybin and Silybin might be suitable candidates to design potent PXR antagonists to prevent drug-drug interactions via CYP3A4 in cancer patients.
Isosilybin A
Catalog No: CFN91070
Isosilybin A is a partial PPARγ agonist, it significantly induced ABCA1 protein expression, it inhibited both monophenolase (IC50 = 1.7-7.6 µM) and diphenolase (IC50 = 12.1-44.9 µM) of tyrosinase. Isosilybin A shows anti-angiogenic efficacy, it has anti-prostate cancer (PCA) activity that is mediated via cell cycle arrest and apoptosis induction.
Isosilybin B
Catalog No: CFN91071
Isosilybin B causes androgen receptor degradation in human prostate carcinoma cells via PI3K-Akt-Mdm2-mediated pathway, it has anti-prostate cancer (PCA) activity that is mediated via cell cycle arrest and apoptosis induction. Isosilybin B showed inhibitory effect on CYP2C8 activity. It inhibited both monophenolase (IC50 = 1.7-7.6 μM) and diphenolase (IC50 = 12.1-44.9 μM) of tyrosinase.
Isosilychristin
Catalog No: CFN95369
Isosilychristin is an antioxidant with multidrug resistance modulating activity. Isosilychristin significantly induces ABCA1 protein expression without affecting cell viability.Isosilychristin has anticancer and hepatoprotective activity.
Isosinensetin
Catalog No: CFN90806
Isosinensetin shows antioxidant and HIV-1 protease inhibiting activities.
Isospinosin
Catalog No: CFN95350
Isosteviol
Catalog No: CFN90544
Isosteviol possesses various biological activities including anti-hyperglycemic, anti-hypertensive, anti-tumor, anti-inflammatory, neuroprotective, antibacterial, antifungal,and antioxidant effects.Isosteviol plays a protective role in a variety of stress-induced cardiac diseases, it can prevent the prolongation of action potential in hypertrophied cardiomyoctyes by regulating transient outward potassium and L-type calcium channels.
Isotachioside
Catalog No: CFN98398
Isotachioside has15-lipoxygenase (15-LO) inhibitory activities.
Isotanshinone I
Catalog No: CFN90356
Isotanshinone I ,neotanshinone A and cryptotanshinone have different effects on inhibiting proteic activity of P38 and NF-κB signaling pathway,and this effect may be one of main mechanisms of inhibitive inflammation reaction by salvia miltiorrhiza bunge in liver.
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