Hot Products

Lucidenic acid E
Catalog No: CFN93125

Reference standards.

Lucidenic acid F
Catalog No: CFN94105

Lucidenic acid F as a modulator of JNK and p38, it shows potent inhibitory effects on EBV-EA induction.

Lucidenic acid SP1 (Lucidenic acid LM1)
Catalog No: CFN92994

Reference standards.

Lucidin
Catalog No: CFN80213

Lucidin and its derivatives are genotoxic, it is mutagenic at the hypoxanthine-guanine phosphoribosyl transferase gene locus.

Lucidone
Catalog No: CFN98011

Lucidone possesses hepatoprotective, antioxidant and anti-inflammatory properties, it-mediated up-regulation of phase-II enzymes and HO-1 via Nrf-2 signaling pathway may provide a pivotal mechanism for its hepatoprotective action. Dietary intake of lucidone alleviates high fat diet-induced obesity in C57BL/6 mice and reveals the potential of lucidone as a nutraceutical to prevent obesity and consequent metabolic disorders. Lucidone accelerates wound healing through the cooperation of keratinocyte/fibroblast/ ndothelial cell growth and migration and macrophage inflammation via PI3K/AKT, Wnt/β-catenin and NF-κB signaling cascade activation. Lucidone also suppresses hepatitis C virus replication by Nrf2-mediated heme oxygenase-1 induction, it could be a potential lead or supplement for the development of new anti-HCV agent in the future.

Lucidone B
Catalog No: CFN91025

Reference standards.

Lucidumol A
Catalog No: CFN95059

Lucidumol A has relatively good effect against aldose reductase with IC50 of 19.1uM. Lucidumol A has cytotoxic activity, it reduced cell growth in three human carcinoma cells (Caco-2, HepG2, and HeLa cells) dose dependently with LC50s from 20.87 to 84.36 uM.

Lumacaftor (VX-809)
Catalog No: CFN60062

VX-809 (Lumacaftor, VRT 826809) acts to correct CFTR mutations common in cystic fibrosis by increasing mutant CFTR (F508del-CFTR) maturation,EC50 of 0.1 μM in fisher rat thyroid cells.

Lupalbigenin
Catalog No: CFN97245

Lupalbigenin sensitizes detachment-induced cell death in human lung cancer cell through down-regulation of pro-survival proteins.Lupalbigenin, laburnetin , and isolupalbigenin show promising cytotoxic effects toward HL-60 cells (IC50 4.3 ± 0.7 to 18.0 ± 1.7 uM).

Lupanine
Catalog No: CFN98924

Lupanine has a weak sedative effect on the central nervous system, interaction with specific drugs used for treatment of the CNS and for analgesic activity. Lupanine improves glucose homeostasis by influencing KATP-channels of pancreatic beta cells.