Isomucronulatol 7-O-glucoside

Isomucronulatol 7-O-glucoside
Product Name Isomucronulatol 7-O-glucoside
CAS No.: 94367-43-8
Catalog No.: CFN93256
Molecular Formula: C23H28O10
Molecular Weight: 464.5 g/mol
Purity: >=98%
Type of Compound: Flavonoids
Physical Desc.: Powder
Targets: MMP13 | COX | TNF-α | p65 | IL Recepter
Source: The roots of Astragalus membranaceus
Solvent: DMSO, Pyridine, Methanol, Ethanol, etc.
Price: $238/10mg
Isomucronulatol 7-O-β-D-glucoside shows anti-osteoarthritic effects, it reduced the expression of all OA-related molecules.
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Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to:

The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
  • Int Immunopharmacol.2020, 90:107268.
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  • Biorxiv2019, 10.1101
  • Toxicological Research2020, doi: 10.1007.
  • Antioxidants (Basel).2020, 9(2):E99
  • Korean Journal of Medicinal Crop Science2018, 26(5):382-390
  • New Zealand J. Forestry Sci.2014, 44:17
  • Ind Crops Prod.2014, 62:173-178
  • Molecules.2020, 25(9):2111.
  • Korean Journal of Pharmacognosy2018, 49(3):270-277
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    Molecules, 2018, 23(11).
    Inhibition of Osteoarthritis-Related Molecules by Isomucronulatol 7-O-β-d-glucoside and Ecliptasaponin A in IL-1β-Stimulated Chondrosarcoma Cell Model.[Reference: WebLink]
    Osteoarthritis (OA) is the common form of arthritis and is characterized by disability and cartilage degradation. Although natural product extracts have been reported to have anti-osteoarthritic effects, the potential bioactivity of Ryupunghwan (RPH), a traditional Korean medicinal botanical formula that contains Astragalus membranaceus, Turnera diffusa, Achyranthes bidentata, Angelica gigas, Eclipta prostrata, Eucommia ulmoides, and Ilex paraguariensis, is not known well. Therefore, the inhibitory effects of single compounds isolated from RPH on the OA-related molecules were investigated using IL-1β-stimulated chondrosarcoma SW1353 (SW1353) cell model.
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    These synergic effects may provide potential molecular modes of action for the anti-osteoarthritic effects of RPH observed in clinical and animal studies.

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