Licoisoflavone B
Catalog No: CFN96405
Licoisoflavone B is an inhibitor of germ tube growth in the arbuscular mycorrhizal (AM) fungus Gigaspora margarita, it can strongly inhibit germ tube growth at 0.63 ug/disc, and it can completely inhibit hyphal branching induced by a lupin strigolactone, orobanchyl acetate, in G. margarita at 0.16 ug/disc. Licoisoflavone B exhibits inhibitory activity against the growth of Helicobacter pylori in vitro, it also shows anti-H. pylori activity against a clarithromycin (CLAR) and amoxicillin (AMOX)-resistant strain.Licoisoflavone B exhibits antimutagenic activity against carcinogenic N-methyl-N-nitrosourea (MNU), it is important to prevent DNA damage by N-nitrosamines for cancer chemoprevention.
Licoricidin
Catalog No: CFN96389
Licoricidin, is a potent anti-metastatic agent, which can markedly inhibit the metastatic and invasive capacity of malignant prostate cancer cells. Licoricidin and licorisoflavan A are effective in inhibiting the growth of all three bacterial species(Porphyromonas gingivalis, Prevotella intermedia and Solobacterium moorei), with minimal inhibitory concentrations in the range of 2-80 ug /ml, they have a potential for reducing bacterial volatile sulfur compounds (VSCs) production and therefore for controlling halitosis; they also have potential for the development of novel host-modulating strategies for the treatment of cytokine and/or MMP-mediated disorders such as periodontitis. Licoricidin may be considered as an active ingredient in new topically applied anti-ageing formulations, it blocks UVA-induced photoaging via ROS scavenging,this activity converges to limit the activity of MMP-1.
