Hot Products

Indirubin
Catalog No: CFN90239

Indirubin is a potent cyclin-dependent kinases and GSK-3β inhibitor with IC50 of about 5 μM and 0.6 μM. Indirubin has anticancer, anti-inflammatory,antiviral,anti-allergic contact dermatitis effects. Each indirubin derivative acts on the DNA binding of NF-Y and represses the MDR1 gene promoter with tumor cell-type specificity.Indirubin derivatives have a potential to be used as an adjunct to antiviral therapy for the treatment of severe human H5N1 disease.

Indole-3-acetic acid
Catalog No: CFN93308

Indole-3-acetic acid , a well-known phytohormone, can also be a signaling molecule in bacteria and therefore can have a direct effect on bacterial physiology.

Indolelactic acid
Catalog No: CFN95263

Indolelactic acid is a phytochormone.

Ingenol
Catalog No: CFN90187

Ingenol derivatives inhibit proliferation and induce apoptosis in breast cancer cell lines, formulating novel derivatives from Ingenol esters may be an innovative approach to develop new lead compounds to reactivate latent HIV. Ingenol mebutate is an effective treatment for actinic keratosis.

Ingenol 3-Angelate
Catalog No: CFN90924

Ingenol-3-angelate shows anticancer activity, and P-gp-mediated absorptive transport, dermal penetration, and vascular damage contribute to the anticancer activity of ingenol-3-angelate in vivo; it activates a broad range of PKC isoforms and induces apoptosis in acute myeloid leukemia cells by activating the PKC isoform PKCdelta. Ingenol-3-angelate suppresses HIV infection of primary CD4+ T cells through down-modulation of cell surface expression of HIV co-receptors. Ingenol-3-angelate emerges as a unique local chemotherapeutic immunostimulatory debulking agent that could be used in conjunction with immunotherapies to promote regression of metastases.

Inokosterone
Catalog No: CFN92515

Inokosterone is an analgesic drug. It also shows high insect moulting hormone activity.

Inosine
Catalog No: CFN93249

Inosine, an endogenous purine nucleoside, has immunomodulatory, neuroprotective, and analgesic properties.Inosine is a cardiotonic agent, can treat cardiac disorders.Inosine can to be capable of forming base pairs with Adenine HFN72-P, Cytosine HDR44-O or Uracil BTP40-U thus contributing to genetic code degeneracy by causing stable mispairings.

Inositol
Catalog No: CFN91718

Inositol is a compound of sugar alcohols. Inositol is involved in a series of biological processes such as insulin signal transduction and cytoskeletal transduction. Inositol mainly exists in glial cells and plays an osmotic role. IC50 & Target: Human Endogenous Metabolite

Inotodiol
Catalog No: CFN92367

Inotodiol shows significant anti-tumor and anti-tumor promoting activities, including human cervical cancer, it inhibits cell proliferation through apoptosis induction by activating caspase-3. Inotodiol can inhibit proliferation and induce the apoptosis of A549 cells, and its molecular mechanism may be associated with the up-regulating expression of p53 and bax proteins and down-regulating expression of Bcl-2 protein, which arrested A549 cells in S phase.

Integerrimine
Catalog No: CFN00419

Prenatal exposure to Integerrimine N-oxide induces maternal toxicity, impairment of maternal care and delayed in physical and behavioral development of the offspring. Doses of Integerrimine N-oxide here employed did not produce marked immunotoxic effects.