Hot Products

Isochlorogenic acid C(4,5)
Catalog No: CFN90354

Isochlorogenic acid C(4,5) has antiviral activity, including anti-HIV-1 integrase activity. It shows anti-hepatotoxic activity.

Isocorynoxeine
Catalog No: CFN98155

Isocorynoxeine, an isorhynchophylline-related alkaloid, exhibits a dose-dependent inhibition of 5-HT2A receptor-mediated current response with an IC50 of 72.4 μM. Isocorynoxeine shows the effects of lowering blood pressure, vasodilatation, and protection against ischemia-induced neuronal damage, it exhibits a significant neuroprotective effect against glutamate-induced HT22 cell death at the maximum concentration.

Isocryptotanshinone
Catalog No: CFN90355

Isocryptotanshinone inhibits protein tyrosine phosphatase 1B (PTP1B) activity with 50% inhibitory concentration values of 56.1±6.3 μM, PTP1B acts as a negative regulator of insulin signaling, and selective inhibition of PTP1B has served as a potential drug target for the treatment of type 2 diabetes.

Isocucurbitacin B
Catalog No: CFN91003

Isocucurbitacin B has significantly activities against HeLa and HT-29 human cancer cells with IC50 values ranging from 0.93 to 9.73uM.

Isocucurbitacin D
Catalog No: CFN95326

Isocucurbitacin D showed a cytotoxic effect with disruption of target protein cofilin. Isocucurbitacin D exhibited the highest activities of improved the LDL uptake rate.Isocucurbitacin D dose-dependently increased LDLR protein levels and decreased PCSK9 protein levels.

Isocupressic acid
Catalog No: CFN99882

Isocupressic acid induces abortion in pregnant cows when ingested primarily during the last trimester, it decrease affects the angiogenesis of the female reproductive system, the decrease in blood flow and apoptosis of corpus luteum-derived endothelial cells of the uterine tissue results in abortion. Isocupressic acid shows strong inhibitory effect on Epstein-Barr virus early antigen (EBV-EA) induction (100 % inhibition at 1000 mol ratio/12-O-tetradecanoylphorbol 13-acetate (TPA).

Isocurcumenol
Catalog No: CFN92618

Isocurcumenol inhibits 5α-reductase which converts testosterone to dihydrotestosterone (DHT).

Isodeoxyelephantopin
Catalog No: CFN97745

Isodeoxyelephantopin exerts antitumor effects on several cancer cells by inducing apoptosis , cell cycle arrest , and inhibiting proliferation. It enhances apoptosis and inhibit invasion and osteoclastogenesis by inhibiting NF-kappaB activation and NF-kappaB-regulated gene expression.

Isoderrone
Catalog No: CFN92794

Isoderrone shows inhibitory effects on α-glucosidase in vitro; it is a protein tyrosine phosphatase 1B (PTP1B) inhibitor, with IC50 value of 22.7 ± 1.7 uM, suggests that it may be a new drug for treatment of type 2 diabetes.

Isodorsmanin A
Catalog No: CFN96199

Reference standards.