Hot Products

Chelerythrine
Catalog No: CFN98449

Chelerythrine is a well-known protein kinase C inhibitor, can inhibit telomerase activity, it also can block the human P2X 7 receptor. Chelerythrine has antimanic, potential antiproliferative and antitumor effects, it has significant cytotoxic effect, independent of p53 and androgen status, on human prostate cancer cell lines.

Chelidimerine
Catalog No: CFN93347

Reference standards.

Chelidonic acid
Catalog No: CFN94111

Chelidonic acid is a component of Chelidonium majus L., used as a mild analgesic, an antimicrobial, an acentral nervous system sedative. Chelidonic acid also shows anti-inflammatory activity. Chelidonic acid has potential to inhibit IL-6 production by blocking NF-κB and caspase-1. Chelidonic acid is a glutamate decarboxylase inhibitor, with a Ki of 1.2 μM.

Chelidonine
Catalog No: CFN90319

Chelidonine is a promising model compound for overcoming MDR and for enhancing cytotoxicity of chemotherapeutics, especially against leukaemia cells, its efficacy needs to be confirmed in animal models. Chelidonine may be a potential therapeutic agent against metastasis of invasive human cancer cells, exhibits anti‑migratory and anti‑invasive effects in MDA‑MB‑231 cells, by suppressing COL‑I‑induced integrin signaling, through inhibiting the formation of the IPP complex and subsequent down‑regulation of IPP downstream signaling molecules, such as Akt and ERK1/2.

Chenodeoxycholic acid
Catalog No: CFN90478

Chenodeoxycholic acid is a hydrophobic primary bile acid that activates nuclear receptors (FXR) involved in cholesterol metabolism. Chenodeoxycholic acid could reverse obesity in cHF-fed mice, mainly in response to the reduction in food intake.

Chicanine
Catalog No: CFN90914

Chicanine has anti-inflammatory activity in macrophages by down-regulating LPS-induced inflammatory cytokines in IκBα/MAPK/ERK signaling pathways. Chicanine also has good anti-proliferation (IC₅₀=44.2uM) on prostate cells and antioxidant activities (IC₅₀=26.0 uM,) with no significant toxic effects on normal cells.

Chicoric acid
Catalog No: CFN99725

Chicoric acid, a new compound able to enhance insulin release and glucose uptake, it is a new potential antidiabetic agent carrying both insulin sensitizing and insulin-secreting properties. Chicoric acid has antiobesity effects, it can induce apoptosis in 3T3-L1 preadipocytes through ROS-mediated PI3K/Akt and MAPK signaling pathways. L-Chicoric acid has antiviral activity against HIV-1, which has been attributed to the inhibition of HIV-1 integration.

Chiisanoside
Catalog No: CFN90571

Chiisanoside has anti-oxidant, anti-inflammatory, anti-rotaviral activities, it can inhibit xanthine oxidase activity and increase superoxide dismutase (SOD), glutathione peroxidase and catalase, it also inhibits NO and PGE2 production. Chiisanoside has the potential to prevent obesity as a lipase inhibitor which suppresses fat absorption in vivo.

Chikusetsusaponin IV
Catalog No: CFN90542

Chikusetsusaponin IV may relieve cutaneous symptoms caused by excessive apoptotic cell death in the skin through the Fas/FasL pathway.

Chikusetsusaponin IVa
Catalog No: CFN92516

Chikusetsusaponin IVa is a novel AMPK activator, can induce insulin secretion from βTC3 cells via GPR40 mediated calcium and PKC pathways, may be developed into a new potential for therapeutic agent used in T2DM patients.Chikusetsusaponin IVa exerts antithrombotic effects, including minor hemorrhagic events.