Sikokianin A
Sikokianin A shows in vitro antiviral activity against HBsAg secretion.
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Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to
24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
Applied Biological Chemistry 2022, 65,5(2022).
J Ethnopharmacol.2016, 192:370-381
Appl Microbiol Biotechnol.2016, 100(9):3965-77
Eur J Pharmacol.2024, 978:176800.
Malaysian J of Fundamental and Applied Sciences 2018, 14(3):368-373
Patanjali Research Foundation2024, ssrn.4807357
Mol Biol Rep.2022, doi: 10.1007
Applied Biological Chem. 2020, 26(63).
J Med Chem.2023, 66(6):4106-4130.
Antimicrob Agents Chemother.2024, e0031424.
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Chem Pharm Bull (Tokyo). 2005 Jul;53(7):776-9.
Antimitotic and antifungal C-3/C-3''-biflavanones from Stellera chamaejasme.[Pubmed:
15997133]
Two new C-3/C-3'' biflavanones, chamaejasmenin D (1) and isochamaejasmenin B (2), were isolated from the roots of Stellera chamaejasme, together with five known biflavanones, chamaejasmenin A (3), chamaejasmenin B (4), neochamaejasmin A (5), Sikokianin A (6), and chamaejasmenin C (7).
METHODS AND RESULTS:
Their structures were elucidated by spectroscopic methods, including 2D NMR techniques. Among these compounds, 1-3 demonstrated potent antimitotic and antifungal activity with minimum inhibitory concentration (MIC) values of 6.25, 6.25, and 3.12 microg/ml, respectively.
Chem Biodivers. 2008 Jul;5(7):1419-24.
Biflavanones, flavonoids, and coumarins from the roots of Stellera chamaejasme and their antiviral effect on hepatitis B virus.[Pubmed:
18649308 ]
A new 3,3''-biflavanone, isoSikokianin A, was isolated from the roots of Stellera chamaejasme, together with eleven known compounds.
METHODS AND RESULTS:
Their structures and configurations were elucidated by spectroscopic methods including 2D-NMR techniques. Sikokianin A, chamaechromone, and quercetin showed in vitro antiviral activity against HBsAg secretion.
