Ruixianglangdusu B
Ruixianglangdusu B exhibits immunomodulatory activity.
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Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to
24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
Nat Commun.2019, 10(1):2745
The Journal of Agromedicine and Medical Sciences2018, 4(1)
Korean Herb. Med. Inf.2020, 8(2):233-242.
Phytomedicine.2022, 100:154085.
Int Immunopharmacol.2020, 90:107268.
Food Analytical Methods2020, 1-10
Molecules.2021, 26(2):313.
Molecules.2024, 29(5):1050.
Int J Mol Sci.2018, 19(9):E2601
Cancer Sci.2022, 113(4):1406-1416.
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Yao Xue Xue Bao. 2001 Sep;36(9):669-71.
New biflavanones and bioactive compounds from Stellera chamaejasme L.[Pubmed:
12580104]
To study the chemical constituents of the root of Stellera chamaejasme L.
METHODS AND RESULTS:
Various column chromatographies on silica gel and RP-18 were employed for isolation and purification. Structures of compounds were elucidated by spectral analysis. Eight lignans and three biflavonoids possessing a C-3/C-3" linkage were isolated. They are ruixianglangdusu A (1) and Ruixianglangdusu B (2), 4',4'",5,5",7,7"-hexahydroxy-3,3"-biflavone (3), (+)-kusunokinin (4), lirioresinol-B (5), magnolenin C (6), (-)-pinoresinol monomethyl ether (7), (-)-pinoresinol (8), (+)-matairesinol (9), isohinokinin (10) and (-)-eudesmin (11).
CONCLUSIONS:
Compounds 1 and 2 are new biflavanones, 1 is enantiomeric to known chamaejasmenin C, 4, 6, 8, 9, 10 and 11 were isolated from this plant for the first time, and 7 was isolated from natural resources for the first time. In vitro bioassays showed that 3 and 8 exhibited antibacterial activity, and 1, 2, 9 and 11 exhibited immunomodulatory activity.
