Shizukolidol
Standard reference
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Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to
24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Tetrahedron Letters.2007 Jan15; 48(3):453–456.
Sesquiterpenoid with new skeleton from Chloranthus henryi.[Reference:
WebLink]
METHODS AND RESULTS:
Dayejijiol (1), a novel sesquiterpene with a new carbon skeleton, and a novel labdane-type diterpenoid (13S)-13-hydroxy-19-methoxy-5αH-8(17), 14-labdadien (3), together with three known compounds chloranthalactone A (4), shizukanolide (5), Shizukolidol (6) were isolated from Chloranthus henryi Hemsl. Their structures were established by a combination of 1D and 2D NMR spectroscopic techniques.
CONCLUSIONS:
Compounds 1 and 5 exhibited anti-tumor activities against Hela and K562 human tumor cell lines.
Nat Prod Res. 2016 Nov;30(21):2476-82.
Two new sesquiterpenes from Chloranthus japonicus Sieb.[Pubmed:
27399937 ]
METHODS AND RESULTS:
Two new sesquiterpenes, namely, 1β,10β-dihydroxy-eremophil-7(11), 8-dien-12,8-olide (1) and 8,12-epoxy-1β-hydroxyeudesm-3,7,11-trien-9-one (2), together with three known sesquiterpenoids, Shizukolidol (3), 4α-hydroxy-5α(H)-8β-methoxy-eudesm-7(11)-en-12,8-olide (4), and neolitacumone B (5), and two known monoterpenes, (3R,4S,6R)-p-menth-1-en-3,6-diol (6) and (R)-p-menth-1-en-4,7-diol (7), were isolated from the whole plant of Chloranthus japonicus Sieb. Their structures were elucidated on the basis of spectroscopic data analysis and comparison with those of related known compounds.
CONCLUSIONS:
Compounds 4-7 were isolated from this plant for the first time.
