Elgonica dimer A
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Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to
24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Yao Xue Xue Bao . 2006 Oct;41(10):1000-1003.
[Active constituents from Aloe arborescens as BACE inhibitors][Pubmed:
17184120]
Aim: To seek for new components as BACE inhibitors from Aloe arborescens.
Methods: The chemical constituents were isolated by chromatographic methods and their structures were elucidated on the basis of spectral analysis.
Results: Eight compounds were isolated and their structures identified as 6'-O-isobutyryl aloenin A (1), aloenin A (2), aloe-emodin (3), (E)-2-acetonyl-8-(2'-O-feruloxyl)-beta-D-glucopyranosyl-7-methoxy-5-methyl-chromone (4), 7-O-methylaloeresin A (5), babarloin A (6), elgonica-dimer A (7), and elgonica-dimer B (8), separately.
Conclusion: Compound 1 is a new compound, and compound 4 was isolated from A. arborescens for the first time. Pharmacological tests indicated that 2, 4, 5 and 6 have moderate inhibitory active on BACE.
Planta Med . 2001 Nov;67(8):757-760.
Hypotensive effect of chemical constituents from Aloe barbadensis[Pubmed:
11731923]
Hypotensive effects of aloeemodin, aloin A, Elgonica dimer A and bisbenzopyran from Aloe barbadensis have been studied. Aloeemodin has emerged as a potent hypotensive agent in current pharmacological investigations and caused 26 %, 52 %, and 79 % falls in mean arterial blood pressure at the corresponding doses of 0.5, 1, and 3 mg/kg in rats. The paper also describes the absolute configuration of Elgonica dimer A (1).
Planta Med . 2001 Nov;67(8):757-760.
Hypotensive effect of chemical constituents from Aloe barbadensis[Pubmed:
11731923]
Hypotensive effects of aloeemodin, aloin A, Elgonica dimer A and bisbenzopyran from Aloe barbadensis have been studied. Aloeemodin has emerged as a potent hypotensive agent in current pharmacological investigations and caused 26 %, 52 %, and 79 % falls in mean arterial blood pressure at the corresponding doses of 0.5, 1, and 3 mg/kg in rats. The paper also describes the absolute configuration of Elgonica dimer A (1).
Yao Xue Xue Bao . 2006 Oct;41(10):1000-1003.
[Active constituents from Aloe arborescens as BACE inhibitors][Pubmed:
17184120]
Aim: To seek for new components as BACE inhibitors from Aloe arborescens.
Methods: The chemical constituents were isolated by chromatographic methods and their structures were elucidated on the basis of spectral analysis.
Results: Eight compounds were isolated and their structures identified as 6'-O-isobutyryl aloenin A (1), aloenin A (2), aloe-emodin (3), (E)-2-acetonyl-8-(2'-O-feruloxyl)-beta-D-glucopyranosyl-7-methoxy-5-methyl-chromone (4), 7-O-methylaloeresin A (5), babarloin A (6), elgonica-dimer A (7), and elgonica-dimer B (8), separately.
Conclusion: Compound 1 is a new compound, and compound 4 was isolated from A. arborescens for the first time. Pharmacological tests indicated that 2, 4, 5 and 6 have moderate inhibitory active on BACE.
