Sepinol
Reference standards.
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Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to
24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Biochemical Pharmacology, 2017, 139:132.
P22 Discovery of new bioactive compounds from (Dioclea reflexa Hook F.): Effective constituents of a traditional herbal medicine.[Reference:
WebLink]
METHODS AND RESULTS:
Three new flavonoids, reflevone 1, lexaflavanone 2 and lexaflavanol 3, together with, mearnsetin 4, 7,4’-dihydroxyflavone 5, Sepinol 6, pallasin 7, 4-OMGA (3, 5-dihydroxyl-4-methoxylbenzoic acid) 8, Lupeol 9, Hederagenin 10 and a rare dipeptide, auratiamide acetate 11 were isolated from the ethyl acetate soluble part of the ethanolic root extract of Dioclea reflexa. Structures of the isolated compounds were elucidated by 1 and 2-dimensional NMR spectroscopy. The secondary metabolites were selectively examined for immunomodulatory, urease inhibitory, lypoxigenase inhibitory and free radical scavenging activities. Additionally, an in vitro cytotoxicity bioassay was carried on human non small cell lung cancer (NCI-H460).
CONCLUSIONS:
Our findings suggest that various activities of the new metabolites may indicate pharmacological potential against immune disorders, gastrointestinal ulcers and oxidative stress diseases.
