Asiaticoside B

Asiaticoside B
Product Name Asiaticoside B
CAS No.: 125265-68-1
Catalog No.: CFN95124
Molecular Formula: C48H78O20
Molecular Weight: 975.13 g/mol
Purity: >=98%
Type of Compound: Triterpenoids
Physical Desc.: Powder
Source: The herbs of Centella asiatica (L.) Urban
Solvent: DMSO, Pyridine, Methanol, Ethanol, etc.
Price: $158/20mg
Asiaticoside B has notable cytotoxicity against HepG2 and MCF-7 cancer cell lines.
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Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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    J Nat Prod. 2006 Oct;69(10):1500-2.
    Cytotoxic cycloartane triterpene saponins from Actaea asiatica.[Pubmed: 17067171 ]

    METHODS AND RESULTS:
    Three new 9,19-cycloartane triterpene glycosides, asiaticoside A (1), Asiaticoside B (2), and 25-O-ethylcimigenol-3-O-beta-D-xylopyranoside (3), together with cimiacemoside I (4), 25-O-acetylcimigenol-3-beta-O-D-xyloside (5), and 25-anhydrocimigenol-beta-O-D-xyloside (6) were isolated from the roots/rhizomes extract of Actaea asiatica, and their structures were established by spectroscopic methods (IR, HRESIMS, and NMR).
    CONCLUSIONS:
    Compounds 1-3, 5, and 6 had notable cytotoxicity against HepG2 and MCF-7 cancer cell lines.
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    METHODS AND RESULTS:
    An improved HPLC qualitative and quantitative method of six triterpenes (asiaticoside, madecassoside, asiatic acid, madecassic acid, terminolic acid, and Asiaticoside B) in Centella asiatica (raw plant material and preparations) is described in this paper. After 50 minutes the six active triterpenes were separated and detected in the methanolic extract at a limit of 0.01 microg/ml.
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