Quasipanaxatriol

Quasipanaxatriol
Product Name Quasipanaxatriol
CAS No.: 171903-78-9
Catalog No.: CFN95248
Molecular Formula: C30H50O3
Molecular Weight: 458.7 g/mol
Purity: >=98%
Type of Compound: Triterpenoids
Physical Desc.: Powder
Source: The roots of Panax ginseng C. A. Mey.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Price: $413/5mg
Quasipanaxatriol can greatly enhance the cytotoxicity of the anti-cancer drugs in P388/ADM cells.
Inquire / Order: manager@chemfaces.com
Technical Inquiries: service@chemfaces.com
Tel: +86-27-84237783
Fax: +86-27-84254680

Address:
1 Building, No. 83, CheCheng Rd., Wuhan Economic and Technological Development Zone, Wuhan, Hubei 430056, PRC
Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
  • Semyung University2017, 149407
  • Oxid Med Cell Longev.2021, 2021:6647107.
  • J Microbiol Biotechnol.2022, 32(2):141-148.
  • J AOAC Int.2021, 104(6):1634-1651.
  • Chemistry of Natural Compounds2019, 55(1):127-130
  • Int J Cosmet Sci.2023, 45(2):155-165.
  • Sci Rep.2023, 13(1):13610.
  • Plant Cell Physiol.2023, 64(7):716-728.
  • Food Res Int.2022, 157:111207.
  • Metabolites.2020, 11(1):E11.
  • Ginsenoside Rg1

    Catalog No: CFN99967
    CAS No: 22427-39-0
    Price: $40/20mg
    Notoginsenoside R1

    Catalog No: CFN99999
    CAS No: 80418-24-2
    Price: $50/20mg
    Ginsenoside Re

    Catalog No: CFN99974
    CAS No: 52286-59-6
    Price: $40/20mg
    Ginsenoside Rd

    Catalog No: CFN99975
    CAS No: 52705-93-8
    Price: $30/20mg
    Notoginsenoside E

    Catalog No: CFN95836
    CAS No: 193976-50-0
    Price: $318/5mg
    Gypenoside XLVI

    Catalog No: CFN93372
    CAS No: 94705-70-1
    Price: $218/10mg
    Ginsenoside F4

    Catalog No: CFN90757
    CAS No: 181225-33-2
    Price: Inquiry(manager@chemfaces.com)
    Quasipanaxatriol

    Catalog No: CFN95248
    CAS No: 171903-78-9
    Price: $413/5mg
    Ginsenoside MC

    Catalog No: CFN95232
    CAS No: 175484-06-7
    Price: $318/10mg
    Gynosaponin I

    Catalog No: CFN96182
    CAS No: 1207861-69-5
    Price: Inquiry(manager@chemfaces.com)
    Planta Med 1995; 61(5): 409-413.
    Reversal of Daunomycin and Vinblastine Resistance in Multidrug-Resistant P388 Leukemia in vitro through Enhanced Cytotoxicity by Triterpenoids.[Reference: WebLink]

    METHODS AND RESULTS:
    Examined in vitro were the effects of some triterpenoids from Panax (Araliaceae) and Glycyrrhiza (Leguminosae) spp. on the sensitivity to daunomycin (DAU) and vinblastine (VBL) of adriamycin (ADM)-resistant P388 leukemia cells (P388/ADM), which were resistant to multiple anticancer drugs. Quasipanaxatriol, 20(S)-protopanaxatriol, ginsenoside Rh2, and compound K greatly enhanced the cytotoxicity of the anti-cancer drugs in P388/ADM cells. The extent of enhancement was different among the triterpene compounds; the 4- to 46-fold increase in DAU cytotoxicity was observed in P388/ADM cells in the presence of non-toxic or marginally toxic concentrations of individual compounds, while those for VBL were in the ratios of 2- to 37-fold. The maximum increase in cytotoxicity was observed with 50 µM Quasipanaxatriol; the resistance indices defined to be the ratios of the IC50 values for P388/ADM and P388 parental cells decreased from 79 to 1.7 and from 180 to 4.9 in the cases of DAU and VBL, respectively.
    CONCLUSIONS:
    The reversal of DAU resistance in P388/ADM by Quasipanaxatriol could be explained by the effective accumulation of the drugs mediated by the DAU-efflux blockage.
    Asiaticoside B

    Catalog No: CFN95124
    CAS No: 125265-68-1
    Price: $158/20mg
    (R)-O-isobutyroyllomatin

    Catalog No: CFN95250
    CAS No: 440094-38-2
    Price: $318/5mg
    Cannabiscitrin

    Catalog No: CFN95278
    CAS No: 520-14-9
    Price: $318/5mg
    Isoengeletin

    Catalog No: CFN95284
    CAS No: 30987-58-7
    Price: $318/5mg
    1-(3',5'-dimethoxy)phenyl-2-[4''-O-beta-D-glucopyranosyl (6->1)-O-alpha-L-rhamnopyranosyl]phenylethane

    Catalog No: CFN95285
    CAS No: 1338076-61-1
    Price: $413/5mg
    Fuzitine

    Catalog No: CFN95337
    CAS No: 142287-96-5
    Price: $318/5mg
    3',4',5',5,7-Pentamethoxyflavanone

    Catalog No: CFN95414
    CAS No: 479672-30-5
    Price: $218/20mg
    Methyl ganoderate A

    Catalog No: CFN95550
    CAS No: 105742-78-7
    Price: $413/5mg
    Nomilinic acid

    Catalog No: CFN95559
    CAS No: 35930-20-2
    Price: $318/5mg
    Ephedrannin A

    Catalog No: CFN95579
    CAS No: 82001-39-6
    Price: $318/5mg