Piperitol
Piperitol has in vitro antioxidant potential, it also exhibits a stronger CNS depressant effect than that of M. rotundifolia.
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Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to
24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Phytotherapy Research, 2010, 4(6):232-234.
CNS activity of Mentha rotundifolia and Mentha longifolia essential oil in mice and rats.[Reference:
WebLink]
METHODS AND RESULTS:
The essential oils of Mentha rotundifolia and Mentha longifolia were analyzed with GC and GC/MS. The major components were rotundifolone (10.4%) and Piperitol (57.6%) in M. rotundifolia , and rotundifolone (33.2%) and diosphenol (47.7%) in M. longifolia. M. longifolia essential oil exhibited a stronger CNS depressant effect than that of M. rotundifolia ; both essential oils were somnifacients.
Journal of Agricultural and Food Chemistry, 2011, 59(7):3214-3219.
Identification of Methanol-Soluble Compounds in Sesame and Evaluation of Antioxidant Potential of Its Lignans.[Reference:
WebLink]
The methanol extract of sesame (Sesamum indicum) seeds was fractionated and purified with the assistance of conventional column chromatography to afford 29 compounds including seven furofuran lignans. Among these isolates, (+)-samin (1) was obtained from the natural source for the first time. In addition, (-)-asarinin (30) and sesamol (31) were generated by oxidative derivation from (+)-sesamolin (2) and (+)-sesamin (3), two abundant lignans found in sesame seeds.
METHODS AND RESULTS:
To evaluate their in vitro antioxidant potential, the seven isolated lignans (1-7) and the two derivatives (30 and 31) were examined for the scavenging activities on DPPH free radicals and superoxide anions. Moreover, the capability of chelating ferrous ions and reducing power of these sesame lignans were also measured.
CONCLUSIONS:
The results suggest that, besides the well-known sesamolin and sesamin, the minor sesame lignans (+)-(7S,8'R,8R)-acuminatolide (5), (-)-Piperitol (6), and (+)-pinoresinol (7) are also adequate active ingredients and may be potential sources for nutritional and pharmacological utilization.
Chinese Traditional and Herbal Drugs, 2009, 40(10):1536-1539.
Chemical constituents in leaves of Piper laetispicum.[Reference:
WebLink]
To study the chemical constituents in the leaves of Piper laetispicum.
METHODS AND RESULTS:
Compounds were separated and purified by silica gel column and macroporous resin. Their structures were identified on the basis of spectral methods. Sixteen compounds were isolated and identified from the leaves of P. laetispicum: (2E, 4E)-N-isobutyl-11-phenylundecadienamide (I), (2E, 4E)-N-isobutyl-15-phenylpentadecadienamide (II). laetispicine (III), (2E, 4E)-N-isobutyl-7-(3′ 4′-methylene-dioxyphenyl) heptadienamide ( IV ) , brachystamide A(V), dihydropipercide ( VI ), pipermacramide A [(2E, 4E)-N-isobutyleicosadienamide, VI], ( + )-spathulenol (VIII), d-sesamin (IX),
Piperitol (X), vitexin(XI), vitexin-2″-O-β-D-glucoside (XII), N-p-coumaroyltyramine (XIII), β-sitosterol (XIV), stigmasterol (XV), and 1-dotriacontanol (XVI).
CONCLUSIONS:
Compounds I and II are isolated for the first time as natural substance, compounds V , VI, and VIII are first isolated from P. laetispicum, compounds XI , XII , and XVI are obtained from the plants of Piper L. for the first time.
