Murraxocin
Murraxocin is an insecticidal coumarin.
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Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to
24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
Sci Rep.2015, 5:13194
J of the Korean Society of Cosmetics and Cosmetology2018, 399-406
Plants.2024, 13(10):1348;
Synthetic and Systems Biotechnology2023, j.synbio.
ACS Pharmacol. Transl. Sci.2022, 5,7,479-490
VNU Journal of Science: Med.& Pharm. Sci.2022, 38(2):2588-1132.
J Hematol Oncol.2018, 11(1):112
Journal of Medical Sciences2024, 44(5):p 222-227.
Planta Med.2024, 2328-2750
Plant Cell Tiss Org2020, 1-16
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Phytother Res. 2006 Jul;20(7):607-9.
Characterization of an insecticidal coumarin from Boenninghausenia albiflora.[Pubmed:
16619334]
METHODS AND RESULTS:
The leaves of Boenninghausenia albiflora afforded an insecticidal coumarin which was identified as Murraxocin (7-methoxy-8-[1'-ethoxy-2'-hydroxy-3'-methyl-but-3'enyl]-coumarin) (1), on the basis of extensive 1- and 2-dimensional NMR experiments. This compound has previously been isolated from Murraya exotica but this is the first report of the full (1)H and (13)C data for this compound. This natural product was evaluated against important forest insect pests and was active against Plecoptera reflexa, Clostera cupreata and Crypsiptya coclesalis at different concentrations varying from 1.0% to 5% w/v. In the crude extract 70% mortality was observed, and for compound 1 80% mortality was observed at a concentration of 1.0% w/v. The percentage of insect mortality increased in a dose-dependent manner.
CONCLUSIONS:
Coumarins are poorly studied insecticides and there is potential to exploit this chemically simple group of natural products.
