Ganoderic acid Df

Ganoderic acid Df
Product Name Ganoderic acid Df
CAS No.: 1352033-73-8
Catalog No.: CFN95514
Molecular Formula: C30H44O7
Molecular Weight: 516.7 g/mol
Purity: >=98%
Type of Compound: Triterpenoids
Physical Desc.: Powder
Source: The fruit body of Ganoderma lucidum
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Price: $318/5mg
Ganoderic acid Df exhibited potent human aldose reductase inhibitory activity, with an IC(50) of 22.8 μM in vitro. Ganoderic acid Df as a potential anticancer agent.
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Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
  • Nat Chem Biol.2018, 14(8):760-763
  • Appl. Sci.2020, 10(4),1304
  • Molecules.2022, 27(7):2360.
  • VNU J Sci: Med. Pharm. Sci.2024, 40(2):21-30.
  • The Journal of Korean Medicine2022, 43(3): 79-93.
  • Heinrich Heine University Dusseldorf2021, 62203.
  • Biomed Pharmacother.2024, 173:116319.
  • Drug Dev Ind Pharm.2024, 50(11):938-951.
  • J Inflamm Res.2022, 15:5347-5359.
  • Front Pharmacol.2021, 12:607403.
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    Ganoderic acid Df, a new triterpenoid with aldose reductase inhibitory activity from the fruiting body of Ganoderma lucidum[Pubmed: 20603199]
    Ganoderic acid Df, a new lanostane-type triterpenoid, was isolated from the fruiting body of Ganoderma lucidum. Its structure was characterized as 7β, 11β-dihydroxy-3, 15, 23-trioxo-5α-lanosta-8-en-26-oic acid by 1D- and 2D-NMR spectra. This compound exhibited potent human aldose reductase inhibitory activity, with an IC(50) of 22.8 μM in vitro. A carboxyl group of this compound's side chain is essential for eliciting inhibitory activity because its methyl ester is much less active.
    Fitoterapia . 2010 Dec;81(8):1033-1036.
    Ganoderic acid Df, a new triterpenoid with aldose reductase inhibitory activity from the fruiting body of Ganoderma lucidum[Pubmed: 20603199]
    Ganoderic acid Df, a new lanostane-type triterpenoid, was isolated from the fruiting body of Ganoderma lucidum. Its structure was characterized as 7β, 11β-dihydroxy-3, 15, 23-trioxo-5α-lanosta-8-en-26-oic acid by 1D- and 2D-NMR spectra. This compound exhibited potent human aldose reductase inhibitory activity, with an IC(50) of 22.8 μM in vitro. A carboxyl group of this compound's side chain is essential for eliciting inhibitory activity because its methyl ester is much less active.
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