Isosalvianolic acid C
Isosalvianolic acid C exhibits more potent activity than probucol except for salvianolic acid F .
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Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to
24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
Front Pharmacol.2021, 12:615157.
Hong Kong Baptist University2023, 048330T.
Nutrients2023, 15(18), 4016.
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Journal of Applied Pharmaceutical Science2022, 0(00), pp:001-007
J Biosci.2020, 45:46.
Naunyn Schmiedebergs Arch Pharmacol.2021, 394(1):107-115.
Natural Product Communications2021, 16(9):1-10.
Antioxidants (Basel).2021, 10(11): 1802.
Chemistry of Natural Compounds2018, 204-206
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J Nat Prod. 2002 May;65(5):745-7.
Anti-lipid-peroxidative principles from Tournefortia sarmentosa.[Pubmed:
12027757]
METHODS AND RESULTS:
Using the inhibition of Cu(2+)-induced low-density-lipoprotein (LDL) peroxidation to direct fractionation, four new benzenoids, tournefolal (1), tournefolic acids A (2) and B (3), and B ethyl ester (4), together with salvianolic acid A (5), Isosalvianolic acid C (6), lithospermic acid (7), salvianolic acid F (8), and rosmarinic acid (9), were isolated from the stems of Tournefortia sarmentosa. The structures of the new compounds 1-4 were elucidated on the basis of spectral and chemical methods. Furthermore, the anti-LDL-peroxidative activity of the isolated compounds was determined.
CONCLUSIONS:
All isolated compounds exhibited more potent activity than probucol except for salvianolic acid F (8).
