Latisxanthone C

Latisxanthone C
Product Name Latisxanthone C
CAS No.: 197447-32-8
Catalog No.: CFN89046
Molecular Formula: C28H30O6
Molecular Weight: 462.54 g/mol
Purity: >=98%
Type of Compound: Xanthones
Physical Desc.: Powder
Source: The twigs of Garcinia nigrolineata.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Price:
Latisxanthone C shows inhibitory effects on Epstein-Barr virus early antigen (EBV-EA) activation induced by 12-O-tetradecanoylphorbol-13-acetate (TPA) in Raji cells, it may be a valuable antitumor promoter.
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Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

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The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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    Cancer Lett. 1998 Oct 23;132(1-2):113-7.
    Xanthones as inhibitors of Epstein-Barr virus activation.[Pubmed: 10397461]

    METHODS AND RESULTS:
    To search for possible antitumor promoters, we carried out a primary screening of 20 xanthones isolated from plants of the Guttiferae family, using their possible inhibitory effects on Epstein-Barr virus early antigen (EBV-EA) activation induced by 12-O-tetradecanoylphorbol-13-acetate (TPA) in Raji cells. Some of these xanthones, namely 1,3,7-trihydroxy-2-(3-methyl-2-butenyl)xanthone (8), dulxanthone B (10) and Latisxanthone C (15), were observed to significantly inhibit the EBV-EA activation.
    CONCLUSIONS:
    The investigation indicated that 8, 10 and 15 might be valuable antitumor promoters.
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