Bijaponicaxanthone C
Bijaponicaxanthone C is a natural product from Hypericum riparium.
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Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to
24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
Exp Mol Med.2020, 52(4):629-642.
Emirates Journal of Food and Agriculture.2022, 34(6): 528-536.
Current Analytical Chemistry2024, 20(8):599-610.
Phytomedicine.2023, 116:154841.
J Biomed Sci.2020, 27(1):60.
Separations2021, 8(6),80.
Pharmaceuticals (Basel).2024, 17(3):341.
J Food Biochem.2021, 45(7):e13774.
Sci Rep. 2017, 12953(7)
Molecules.2022, 27(22):7887.
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Records of Natural Products, 2013, 7(1):65-68.
Chemical Constituents, Antimicrobial and Cytotoxic Activities of Hypericum riparium (Guttiferae[Reference:
WebLink]
METHODS AND RESULTS:
Betulinic acid (1), 5-hydroxy-3-methoxyxanthone (2), 1,6-dihydroxy-7-methoxyxanthone (3), daucosterol (4), Bijaponicaxanthone C (5), hypercalin C (6), 1-hydroxy-6,7-dimethoxyxanthone (7), cadensin D (8) and 5-hydroxy-1,3-dimethoxyxanthone (9) were isolated from the roots of Hypericum riparium. These compounds are reported for the first time from this plant.
CONCLUSIONS:
The extracts and two of the isolated compounds (2 and 8) exhibited both antibacterial and antifungal activities that varied between the microbial species (MIC = 0.97-250 μg/mL). In addition, the brine-shrimp (Artemia salina) lethality bioassay of compound 6 showed potent cytotoxicity with LD50 of 3.23 μg/mL.
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