Desmethoxycentaureidin

Desmethoxycentaureidin
Product Name Desmethoxycentaureidin
CAS No.: 22934-99-2
Catalog No.: CFN98234
Molecular Formula: C17H14O7
Molecular Weight: 330.3 g/mol
Purity: >=98%
Type of Compound: Flavonoids
Physical Desc.: Yeollow powder
Source: The herbs of Lippia dulcis Trev.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Price:
Desmethoxycentaureidin shows high inhibitory activity against HeLa cell growth (GI50 9 microM).
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Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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  • Int J Mol Med.2016, 37(2):501-8
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  • Chinese Pharmacological Bulletin2019, 35(8):1120-1125
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    Biol Pharm Bull. 2002 Jul;25(7):920-2.
    Antiproliferative constituents in plants 9. Aerial parts of Lippia dulcis and Lippia canescens.[Pubmed: 12132670]
    Three flavones [Desmethoxycentaureidin (10), eupafolin (11), and 6-hydroxyluteolin (12)] from the latter.
    METHODS AND RESULTS:
    Antiproliferative activity of the isolated compounds against murine melanoma (B16F10), human gastric adenocarcinoma (MK-1), and human uterine carcinoma (HeLa) cells was estimated. (+)-Anymol (3), acteoside (4), isoacteoside (5), arenarioside (8), eupafolin (11), and 6-hydroxyluteolin (12) had GI50 values of 10-16 microM against B16F10 cell. Desmethoxycentaureidin (10) and eupafolin (11) showed high inhibitory activity against HeLa cell growth (GI50 9 microM, and 6 microM, respectively).
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