Cyclo(Pro-Trp)

Cyclo(Pro-Trp)
Product Name Cyclo(Pro-Trp)
CAS No.: 67889-75-2
Catalog No.: CFN90277
Molecular Formula: C16H17N3O2
Molecular Weight: 283.33 g/mol
Purity: >=98%
Type of Compound: Alkaloids
Physical Desc.: Powder
Targets: Antifection
Source: From Pantoea agglomerans
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Price: $238/10mg
Cyclo(Pro-Trp) and cyclo(Phe-Pro) show broad spectrum antibacterial properties.
Inquire / Order: manager@chemfaces.com
Technical Inquiries: service@chemfaces.com
Tel: +86-27-84237783
Fax: +86-27-84254680

Address:
1 Building, No. 83, CheCheng Rd., Wuhan Economic and Technological Development Zone, Wuhan, Hubei 430056, PRC
Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
  • Horticulturae2023, 9(2), 213.
  • J Food Composition and Analysis2022, 104417.
  • Food Chem.2019, 290:286-294
  • Sains Malaysiana2024, 53(2):397-408.
  • J Pharm Biomed Anal.2024, 247:116257.
  • Biol Pharm Bull.2018, 41(1):65-72
  • Chemistry of Plant Raw Materials2019, 4:135-147
  • Industrial Crops and Products2022, 186:115298
  • Front Pharmacol.2021, 12:607403.
  • Int J Mol Sci.2023, 24(8):7300.
  • Cyclo(Phe-Hpro)

    Catalog No: CFN90280
    CAS No: 1016899-94-7
    Price: $238/10mg
    Cyclo(Tyr-Hpro)

    Catalog No: CFN90279
    CAS No: 813461-21-1
    Price: $238/10mg
    Cyclo(Pro-Trp)

    Catalog No: CFN90277
    CAS No: 67889-75-2
    Price: $238/10mg
    Demethoxyfumitremorgin C

    Catalog No: CFN96937
    CAS No: 111768-16-2
    Price: Inquiry(manager@chemfaces.com)
    Fumitremorgin C

    Catalog No: CFN96930
    CAS No: 118974-02-0
    Price: Inquiry(manager@chemfaces.com)
    Fumitremorgin B

    Catalog No: CFN89011
    CAS No: 12626-17-4
    Price: Inquiry(manager@chemfaces.com)
    Heterophyllin B

    Catalog No: CFN90627
    CAS No: 145459-19-4
    Price: $268/20mg
    Rubiyunnanin C

    Catalog No: CFN91927
    CAS No: 1261030-04-9
    Price: Inquiry(manager@chemfaces.com)
    Astin A

    Catalog No: CFN95187
    CAS No: 151201-75-1
    Price: $318/10mg
    Astin B

    Catalog No: CFN95188
    CAS No: 151201-76-2
    Price: $318/10mg
    Pharmazie. 1999 Oct;54(10):772-5.
    Antimicrobial activity of selected cyclic dipeptides.[Pubmed: 10563376]
    Cyclic dipeptides are products of rational drug design, which may exhibit both antimicrobial and antitumor properties. The aim of this study was to investigate both the antimicrobial effects of the cyclic dipeptides cyclo(L-phenylalanyl-L-prolyl), cyclo(L-tyrosyl-L-prolyl), cyclo(L-tryptophanyl-L-prolyl) and cyclo(L-tryptophanyl-L-tryptophanyl) and the effects of these cyclic dipeptides on the gastrointestinal epithelium in vitro. Furthermore, a relevant solvent for the possible pharmaceutical application of the products was sought concurrently.
    METHODS AND RESULTS:
    The antimicrobial effect of the cyclic dipeptides was assayed using the Kirby-Bauer disc diffusion assay against Escherichia coli, Pseudomonas aeruginosa, Klebsiella pneumoniae, Staphylococcus aureus, Bacillus subtilis, Streptococcus pneumoniae, Candida albicans, Aspergillus niger and Penicillium notatum. The effect of the cyclic dipeptides on the gastrointestinal epithelium was assessed by changes in alkaline phosphatase expression of HT-29 cells. Cyclo(Pro-Trp) and cyclo(Phe-Pro) show broad spectrum antibacterial properties and cyclo(Trp-Pro) and cyclo(Trp-Trp) show broad spectrum antifungal properties. The maturation of the gastrointestinal cells was enhanced by cyclo(Phe-Pro), cyclo(Tyr-Pro), cyclo(Trp-Trp) and cyclo(Trp-Pro).
    CONCLUSIONS:
    The activity of these cyclic dipeptides thus indicates potential application of these compounds as pharmacological agents.
    Poricoic acid B

    Catalog No: CFN95050
    CAS No: 137551-39-4
    Price: $318/20mg
    Lappaol A

    Catalog No: CFN95067
    CAS No: 62333-08-8
    Price: $333/10mg
    7,2',4'-Trihydroxy-5-methoxy-3-arylcoumarin

    Catalog No: CFN95070
    CAS No: 1092952-62-9
    Price: Inquiry(manager@chemfaces.com)
    1,3,6-Trihydroxy-2-methylanthraquinone 3-O-alpha-L-rhamnosyl-(1->2)-beta-D-glucoside

    Catalog No: CFN95096
    CAS No: 87686-88-2
    Price: $318/10mg
    Genistein 7-O-beta-D-glucopyranoside-4'-O-[alpha-L-rhamnopyranosyl-(1->2)-beta-D-glucopyranoside]

    Catalog No: CFN95159
    CAS No: 70404-42-1
    Price: $318/10mg
    Biatractylolide

    Catalog No: CFN95205
    CAS No: 182426-37-5
    Price: $268/10mg
    Grosvenorin 2''-glucoside

    Catalog No: CFN95282
    CAS No: N/A
    Price: $318/5mg
    Isospinosin

    Catalog No: CFN95350
    CAS No: 89701-83-7
    Price: $318/5mg
    1,3,4,6-Tetragalloylglucose

    Catalog No: CFN95425
    CAS No: 26922-99-6
    Price: $318/10mg
    Jacquilenin

    Catalog No: CFN95434
    CAS No: 7726-34-3
    Price: $318/5mg