Corynoxidine

Corynoxidine
Product Name Corynoxidine
CAS No.: 57906-85-1
Catalog No.: CFN96484
Molecular Formula: C21H25NO5
Molecular Weight: 371.4 g/mol
Purity: >=98%
Type of Compound: Alkaloids
Physical Desc.: Powder
Targets: Antifection | AChR
Source: The roots of Stephania epigaea.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Price: $288/20mg
Corynoxidine exhibits antibacterial activities against Staphylococcus aureus and methicillin-resistant S. aureus strains. It inhibits acetylcholinesterase activity in a dose-dependent manner, and the IC50 value of 89.0 microM.
Inquire / Order: manager@chemfaces.com
Technical Inquiries: service@chemfaces.com
Tel: +86-27-84237783
Fax: +86-27-84254680

Address:
1 Building, No. 83, CheCheng Rd., Wuhan Economic and Technological Development Zone, Wuhan, Hubei 430056, PRC
Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
  • Phytomedicine.2019, 55:229-237
  • J Ethnopharmacol.2024, 318:116863.
  • J AOAC Int.2024, qsae028.
  • J Appl Microbiol.2024, 135(7):lxae180.
  • Molecules.2024, 29(5):1050.
  • Phytomedicine.2019, 57:95-104
  • Prev Nutr Food Sci.2024, 29(4):504-511.
  • J of the Korean Society of Food Science and Nutrition2019, 32(2):148-154
  • Recent Pat Anticancer Drug Discov.2022, 17(4):416-426.
  • Journal of Chromatography A2020, 460942
  • Tetrahydrocoptisine

    Catalog No: CFN90416
    CAS No: 7461-02-1
    Price: $168/20mg
    Stylopine hydrochloride

    Catalog No: CFN96656
    CAS No: 96087-21-7
    Price: Inquiry(manager@chemfaces.com)
    L-Stepholidine

    Catalog No: CFN90457
    CAS No: 16562-13-3
    Price: $318/20mg
    Scoulerine

    Catalog No: CFN96330
    CAS No: 6451-73-6
    Price: Inquiry(manager@chemfaces.com)
    Tetrahydroberberine

    Catalog No: CFN90506
    CAS No: 522-97-4
    Price: $30/20mg
    Cheilanthifoline

    Catalog No: CFN90945
    CAS No: 483-44-3
    Price: $318/10mg
    Tetrahydroepiberberine

    Catalog No: CFN90507
    CAS No: 38853-67-7
    Price: $238/10mg
    Corypalmine

    Catalog No: CFN97021
    CAS No: 6018-40-2
    Price: $318/5mg
    (-)-Isocorypalmine

    Catalog No: CFN90582
    CAS No: 483-34-1
    Price: $348/10mg
    Steponine

    Catalog No: CFN95926
    CAS No: 17132-69-3
    Price: $318/20mg
    J Asian Nat Prod Res. 2013;15(3):315-8.
    A new antibacterial denitroaristolochic acid from the tubers of Stephania succifera.[Pubmed: 23418880 ]

    METHODS AND RESULTS:
    A new denitroaristolochic acid, demethylaristofolin C (1), together with six known alkaloids, crebanine N-oxide (2), (-)-sukhodianine-β-N-oxide (3), palmatine (4), corydalmine (5), dehydrocorydalmine (6), and Corynoxidine (7), was isolated from the tubers of Stephania succifera. The structure of demethylaristofolin C was elucidated by spectroscopic techniques (UV, IR, 1D, and 2D NMR) and HR-ESI-MS analyses.
    CONCLUSIONS:
    These compounds exhibited antibacterial activities against Staphylococcus aureus and methicillin-resistant S. aureus strains in different degrees.
    Arch Pharm Res. 2004 Nov;27(11):1127-31.
    Acetylcholinesterase inhibitors from the aerial parts of Corydalis speciosa.[Pubmed: 15595415]

    METHODS AND RESULTS:
    In a bioassay-guided search for acetylcholinesterase inhibitors from Korean natural resources, four isoquinoline alkaloids, Corynoxidine (1), protopine (2), palmatine (3), and berberine (4) have been isolated from the methanolic extract of the aerial parts of Corydalis speciosa. Structures of these compounds were elucidated on the basis of spectroscopic techniques.
    CONCLUSIONS:
    These compounds inhibited acetylcholinesterase activity in a dose-dependent manner, and the IC50 values of compounds 1-4 were 89.0, 16.1, 5.8, and 3.3 microM, respectively.
    Secologanic acid

    Catalog No: CFN95028
    CAS No: 60077-46-5
    Price: $318/20mg
    Lonicerin

    Catalog No: CFN95055
    CAS No: 25694-72-8
    Price: $168/10mg
    Caraganaphenol A

    Catalog No: CFN95093
    CAS No: 174916-31-5
    Price: $333/5mg
    Yuanhunine

    Catalog No: CFN95179
    CAS No: 104387-15-7
    Price: $368/5mg
    (E)-6-O-(p-coumaroyl)scandoside methyl ester

    Catalog No: CFN95192
    CAS No: 83946-90-1
    Price: $218/10mg
    3-Hydroxy-4',5-dimethoxystilbene

    Catalog No: CFN95199
    CAS No: 58436-29-6
    Price: $318/10mg
    Eriodictyol 7-O-glucuronide

    Catalog No: CFN95290
    CAS No: 125535-06-0
    Price: $318/10mg
    Physalin X

    Catalog No: CFN95329
    CAS No: 72497-31-5
    Price: $318/5mg
    1,3,4,6-Tetragalloylglucose

    Catalog No: CFN95425
    CAS No: 26922-99-6
    Price: $318/10mg
    Isosecotanapartholide

    Catalog No: CFN95471
    CAS No: 102926-01-2
    Price: $318/10mg