Cheilanthifoline

Cheilanthifoline
Product Name Cheilanthifoline
CAS No.: 483-44-3
Catalog No.: CFN90945
Molecular Formula: C19H19NO4
Molecular Weight: 325.36 g/mol
Purity: >=98%
Type of Compound: Miscellaneous
Physical Desc.: Powder
Targets: NF-kB | Antifection
Source: The rhizomes of Sinomenium acutum.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Price: $318/10mg
Cheilanthifoline has anti-osteoclastogenic property, it gives significant inhibitions on receptor activator of nuclear factor-κB ligand-induced differentiation of mouse bone marrow-derived macrophages into multinucleated osteoclasts. Cheilanthifoline also shows promising in vitro antiplasmodial activities against Plasmodium falciparum.
Inquire / Order: manager@chemfaces.com
Technical Inquiries: service@chemfaces.com
Tel: +86-27-84237783
Fax: +86-27-84254680

Address:
1 Building, No. 83, CheCheng Rd., Wuhan Economic and Technological Development Zone, Wuhan, Hubei 430056, PRC
Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
  • Anticancer Res.2020, 40(10):5529-5538.
  • Agronomy2023, 13(9), 2410.
  • Antioxidants2022, 11(2),234.
  • Int J Mol Sci.2022, 23(21):12816.
  • Metabolites.2019, 9(11):E271
  • Chemistry of Natural Compounds2020, 56,423-426
  • Front Plant Sci.2023, 14:1207940.
  • Functional Ecology2020, doi: 10.1111.
  • Microchemical Journal2018, 137:168-173
  • Aging (Albany NY).2021, 13(19):22867-22882.
  • D-Tetrahydropalmatine

    Catalog No: CFN90188
    CAS No: 3520-14-7
    Price: $118/20mg
    Tetrahydrocoptisine

    Catalog No: CFN90416
    CAS No: 7461-02-1
    Price: $168/20mg
    Stylopine hydrochloride

    Catalog No: CFN96656
    CAS No: 96087-21-7
    Price: Inquiry(manager@chemfaces.com)
    L-Stepholidine

    Catalog No: CFN90457
    CAS No: 16562-13-3
    Price: $318/20mg
    Scoulerine

    Catalog No: CFN96330
    CAS No: 6451-73-6
    Price: Inquiry(manager@chemfaces.com)
    Tetrahydroberberine

    Catalog No: CFN90506
    CAS No: 522-97-4
    Price: $30/20mg
    Cheilanthifoline

    Catalog No: CFN90945
    CAS No: 483-44-3
    Price: $318/10mg
    Tetrahydroepiberberine

    Catalog No: CFN90507
    CAS No: 38853-67-7
    Price: $238/10mg
    Corypalmine

    Catalog No: CFN97021
    CAS No: 6018-40-2
    Price: $318/5mg
    (-)-Isocorypalmine

    Catalog No: CFN90582
    CAS No: 483-34-1
    Price: $348/10mg
    Arch Pharm Res. 2016 May;39(5):713-20.
    Anti-osteoclastogenic effects of isoquinoline alkaloids from the rhizome extract of Sinomenium acutum.[Pubmed: 26992921 ]

    METHODS AND RESULTS:
    A phytochemical investigation for the rhizome extract from Sinomenium acutum (Menispermaceae) resulted in the isolation of several active principles responsible for the anti-osteoclastogenic property of the extract, together with related isoquinoline alkaloids (1-13) including two new compounds, 1 and 2. Among isolated compounds, salutaridine (7), dauricumine (10), Cheilanthifoline (12), and dauriporphine (13) were observed to give significant inhibitions on receptor activator of nuclear factor-κB ligand-induced differentiation of mouse bone marrow-derived macrophages into multinucleated osteoclasts, respectively.
    CONCLUSIONS:
    The chemical structures of two newly isolated compounds, 1 and 2 were established as 8-demethoxycephatonine (1) and 7(R)-7,8-dihydrosinomenine (2), by spectroscopic analyses including 2D NMR experiments.
    Phytother Res. 2010 Apr;24(4):481-5.
    Antiplasmodial agents from the Bhutanese medicinal plant Corydalis calliantha.[Pubmed: 19496064 ]
    The alkaloidal components of the Bhutanese medicinal plant Corydalis calliantha Long, which is used for the treatment of malaria, have been assessed.
    METHODS AND RESULTS:
    Four known alkaloids, protopine (1), scoulerine (2), Cheilanthifoline (3) and stylopine (4) are reported from this plant for the first time. The protopine alkaloid, protopine, and the tetrahydroprotoberine alkaloid, Cheilanthifoline, showed promising in vitro antiplasmodial activities against Plasmodium falciparum, both wild type (TM4) and multidrug resistant (K1) strains with IC(50) values in the range of 2.78-4.29 microM. Such activity had not been demonstrated previously for Cheilanthifoline.
    CONCLUSIONS:
    The results thus support, at a molecular level, the clinical use of this plant in the Bhutanese traditional medicine and identified Cheilanthifoline as a potential new antimalarial drug lead.
    6-Hydroxywogonin

    Catalog No: CFN95009
    CAS No: 76844-70-7
    Price: $368/5mg
    7,2',4'-Trihydroxy-5-methoxy-3-arylcoumarin

    Catalog No: CFN95070
    CAS No: 1092952-62-9
    Price: Inquiry(manager@chemfaces.com)
    Prionanthoside

    Catalog No: CFN95206
    CAS No: 161842-81-5
    Price: $318/10mg
    (-)-Cadin-4,10(15)-dien-11-oic acid

    Catalog No: CFN95246
    CAS No: 1124353-23-6
    Price: $318/5mg
    7-O-(4-beta-D-glucopyranosyloxy-3-methoxybenzoyl)secologanolic acid

    Catalog No: CFN95365
    CAS No: 469899-55-6
    Price: $368/5mg
    (Z)-3,11-dimethy-7-methylene-9,14-epoxy-1,6,10-dodecatrien-3-ol

    Catalog No: CFN95402
    CAS No: 1392202-57-1
    Price: $318/10mg
    Norwogonin-8-O-glucuronide

    Catalog No: CFN95423
    CAS No: 118525-47-6
    Price: $368/5mg
    Fragransin B1

    Catalog No: CFN95443
    CAS No: 112516-03-7
    Price: $318/5mg
    Barbaloin-related compound A

    Catalog No: CFN95453
    CAS No: 473225-21-7
    Price: $318/5mg
    Protocatechuic acid 4-O-beta-glucoside

    Catalog No: CFN95557
    CAS No: 7361-59-3
    Price: $413/5mg