Carbazole
Some carbazole derivatives show antibacterial and antifungal activities.
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Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to
24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
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The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Bioorg Med Chem Lett. 2010 Mar 15;20(6):1881-4.
Synthesis, antibacterial and antifungal activities of some carbazole derivatives.[Pubmed:
20176480 ]
METHODS AND RESULTS:
A series of N-substituted Carbazole derivatives were synthesized and evaluated for antibacterial and antifungal activities against Staphylococcus aureus, methicillin-resistant Staphylococcus aureus (MRSA), Bacillus subtilis, Escherichia coli, Pseudomonas aeruginosa, Bacillus proteus, Candida albicans and Aspergillus fumigatus by two fold serial dilution technique.
CONCLUSIONS:
Some of the synthesized compounds displayed comparable or even better antibacterial and antifungal activities than reference drugs fluconazole, chloramphenicol and norfloxacin against tested strains.
Soil Science Society of America Journal, 1989, 53(5):1391-1401.
Carbazole Sorption by Surface and Subsurface Materials: Influence of Sorbent and Solvent Properties[Reference:
WebLink]
METHODS AND RESULTS:
Sorption of 9H-Carbazole was investigated from aqueous and cosolvent solutions on soils with different physical and chemical properties. Sorption was nonlinear, but well correlated to the organic carbon (OC) content of the soils.
CONCLUSIONS:
For a given solvent (i.e., MeOH, acetone) the log-linear behavior is independent of sorbent properties and exhibits a common slope, thus attesting to the importance of the solvent interaction. In contrast, pyridine as a cosolvent is actively sorbed by some soils creating a more oleophilic surface and a tendency to increase Carbazole partitioning to the soil surface.
J Am Chem Soc. 2004 Jun 23;126(24):7718-27.
Carbazole compounds as host materials for triplet emitters in organic light-emitting diodes: polymer hosts for high-efficiency light-emitting diodes.[Pubmed:
15198620 ]
METHODS AND RESULTS:
A Carbazole homopolymer and Carbazole copolymers based on 9,9'-dialkyl-[3,3']-bicarbazolyl, 2,5-diphenyl-[1,3,4]-oxadiazole and 9,9-bis(4-[3,7-dimethyloctyloxy]phenyl)fluorene were synthesized and their electrical and photophysical properties were characterized with respect to their application as host in phosphorescent polymer light-emitting diodes. It is shown that the triplet energy of a polymer depends on the specific connections between its building blocks. Without changing the composition of the polymer, its triplet energy can be increased from 2.3 to 2.6 eV by changing the way in which the different building blocks are coupled together. For poly(9-vinylCarbazole) (PVK), a Carbazole polymer often used as host for high-energy triplet emitters in polymer light-emitting diodes, a large hole-injection barrier of about 1 eV exists due to the low-lying HOMO level of PVK. For all Carbazole polymers presented here, the HOMO levels are much closer to the Fermi level of a commonly used anode such as ITO and/or a commonly used hole-injection layer such as PEDOT:PSS. This makes high current densities and consequently high luminance levels possible at moderate applied voltages in polymer light-emitting diodes.
CONCLUSIONS:
A double-layer polymer light-emitting diode is constructed comprising a PEDOT:PSS layer as hole-injection layer and a Carbazole-oxadiazole copolymer doped with a green triplet emitter as emissive layer that shows an efficacy of 23 cd/A independent of current density and light output.
