Clausine Z | CAS:866111-14-0 | Manufacturer ChemFaces

Clausine Z exhibits inhibitory activity against cyclin-dependent kinase 5 (CDK5) and shows protective effects on cerebellar granule neurons in vitro.

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Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

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Clausine Z, a new carbazole alkaloid from Clausena excavata with inhibitory activity on CDK5.[Pubmed: 16124414]

METHODS AND RESULTS:
A new carbazole alkaloid, named Clausine Z, has been isolated from the stems and leaves of Clausena excavata Burm. (Rutaceae). Its structure was established by spectroscopic methods.
CONCLUSIONS:
The compound exhibits inhibitory activity against cyclin-dependent kinase 5 (CDK5) and shows protective effects on cerebellar granule neurons in vitro.

Product Name	Clausine Z
CAS No.:	866111-14-0
Catalog No.:	CFN97428
Molecular Formula:	C₁₃H₉NO₃
Molecular Weight:	227.2 g/mol
Purity:	>=98%
Type of Compound:	Alkaloids
Physical Desc.:	Powder
Targets:	CDK
Source:	The herbs of Clausena excavata
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
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