Apigenin 4'-O-rhamnoside
Apigenin-4'-O-rhamnosylglucoside can strongly inhibit the classical pathway of the complement system.
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Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to
24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
Journal of Food and Drug Analysis2023, 31(3), 9.
Manomaniam Sundaranar University2023, 3859769.
Antioxidants (Basel).2021, 10(8):1300.
Phytomedicine.2019, 59:152785
Biology (Basel).2020, 9(11):363.
J Biochem Mol Toxicol.2017, 31(9)
Int J Mol Sci.2018, 19(2)
J Cell Mol Med.2023, 27(10):1423-1435.
Molecules2022, 27(12):3903.
Front Mol Neurosci.2023, 15:1083189.
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Pharmazie. 1996 Oct;51(10):765-8.
In vitro anti-complementary activity of flavonoids from olive (Olea europaea L.) leaves.[Pubmed:
8941947]
METHODS AND RESULTS:
From extracts of olive (Olea europaea L., Oleaceae) leaves showing anti-complementary activity, the flavonoids apigenin, apigenin-4'-O-rhamnosylglucoside, apigenin-7-O-glucoside, luteolin, luteolin-4'-O-glucoside, luteolin-7-O-glucoside, chrysoeriol, chrysoeriol-7-O-glucoside and quercetin-3-O-rhamnoside were isolated.
CONCLUSIONS:
Major isolated constituents strongly inhibited the classical pathway of the complement system.
