8-Hydroxybergapten

Structure
8-Hydroxybergapten
Summary
Product Name 8-Hydroxybergapten
CAS No.: 1603-47-0
Catalog No.: CFN90591
Molecular Formula: C12H8O5
Molecular Weight: 232.19 g/mol
Purity: >=98%
Type of Compound: Coumarins
Physical Desc.: Powder
Source: The roots of Angelica dahurica.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Price: $288/10mg
Description
8-Hydroxybergapten may have anti-wrinkle activity.
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Storage
Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

After receiving
The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
Product Use Citation
  • Appl. Sci.2021, 11(24),12080
  • BMC Microbiol.2019, 19(1):78
  • J Cell Biochem.2024, 125(4):e30537.
  • Drug Chem Toxicol.2024,1-12.
  • Food Res Int.2020, 133:109130.
  • Int J Mol Sci.2021, 22(8):4211.
  • Molecules.2024, 29(11):2626.
  • Front Microbiol.2019, 10:2806
  • J Ethnopharmacol.2024, 320:117426.
  • iScience.2024, 27(8):110496.
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    In vitro
    Journal of the Society of Cosmetic Scientists of Korea, 2005,31(3):227-35.
    Effect of Angelica. against Skin Photo-aging.[Reference: WebLink]
    Skin aging is not a disease nor an abnormal phenomenon but a collection of degenerative changes with age, characterized by skin dryness, wrinkle formation, and loss of skin elasticity.
    METHODS AND RESULTS:
    The skin wrinkles are caused by either genetically predisposed factors or environmental factors such as UV irradiation or physical/chemical stimulus. The histological manifestations of wrinkles are changes in both amount and integrity of elastic and collagen fibers.
    CONCLUSIONS:
    Here we report the isolation and characterization of 3 active compounds, prangenidin, 8-Hydroxybergapten, and xanthotoxol from Angelica dahurica root. The anti-wrinkle activities of these compounds were also investigated.
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