6alpha-Hydroxylycopodine
6alpha-Hydroxylycopodine is a natural product from Phlegmariurus fargesii.
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Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to
24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
Biochem Pharmacol.2020, 178:114083
Molecules.2019, 24(4):E709
The Journal of Animal & Plant Sciences.2020, 30(6):1366-1373
OENO One2023, 57:3.
National Academy Science Letters2023, s40009.
Int J Mol Sci.2021, 22(9):5012.
Nature Ecology & Evolution2020, doi: 10.1038
Biochem Biophys Res Commun.2018, 505(4):1148-1153
Korean Herb. Med. Inf. 2016, 4(1):35-42
Drug Invention Today2019, 12(6):1303-1306
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Chin J Nat Med. 2014 May;12(5):373-6.
A new Lycopodium alkaloid from Phlegmariurus fargesii.[Pubmed:
24856761 ]
To investigate the chemical constituents from the whole plants of Phlegmariurus fargesii.
METHODS AND RESULTS:
Compounds were isolated by repeated silica gel column chromatography. Their structures were elucidated by spectroscopic methods and chemical correlation. The acetylcholinesterase (AChE) inhibitory activity of the isolated compounds was evaluated. A new Lycopodium alkaloid, lycopodine N-oxide (1), along with lycopodine (2), 8,15-dehydrolycopodine (3), 6alpha-Hydroxylycopodine(4), deacetyllycoclavine (5), N-methylhuperzine B (6), lycodine (7), and phlegmarine (8), was isolated.
CONCLUSIONS:
Compound 1 is a new Lycopodium alkaloid, and compound 3 was obtained from nature for the first time. Other alkaloids are isolated from this plant for the first time.
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