6-Ethoxydihydrosanguinarine

6-Ethoxydihydrosanguinarine
Product Name 6-Ethoxydihydrosanguinarine
CAS No.: 28342-31-6
Catalog No.: CFN89308
Molecular Formula: C22H19NO5
Molecular Weight: 377.39 g/mol
Purity: >=98%
Type of Compound: Alkaloids
Physical Desc.: Powder
Targets: AChR | BACE
Source: The roots and aerial parts of Chelidonium majus L.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Price: $268/10mg
6-Ethoxydihydrosanguinarine shows human blood acetylcholinesterase (HuAChE) and human plasma butyrylcholinesterase (HuBuChE) inhibitory activity, with IC50 values of 0.83 +/- 0.04 microM and 4.20 +/- 0.19 microM, respectively.
Inquire / Order: manager@chemfaces.com
Technical Inquiries: service@chemfaces.com
Tel: +86-27-84237783
Fax: +86-27-84254680

Address:
1 Building, No. 83, CheCheng Rd., Wuhan Economic and Technological Development Zone, Wuhan, Hubei 430056, PRC
Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
  • Phytomedicine.2021, 83:153483.
  • Biomed Pharmacother.2019, 111:262-269
  • Front Immunol.2023, 14:1240800.
  • Turkish Journal of Pharmaceutical Sciences2022, DOI: 10.4274
  • Antioxidants (Basel).2020, 9(4):284.
  • Front Plant Sci.2020, 10:1705
  • Am J Chin Med.2015, 30:1-22
  • Int J Mol Sci.2020, 21(8):2790.
  • International Food Research Journal2018, 25(6):2560-2571
  • Applied Biological Chemistry 2022, 65,5(2022).
  • Chelerythrine

    Catalog No: CFN98449
    CAS No: 34316-15-9
    Price: $40/20mg
    Bocconoline

    Catalog No: CFN95373
    CAS No: 32906-88-0
    Price: $413/5mg
    6-Acetonyl-N-methyl-dihydrodecarine

    Catalog No: CFN99367
    CAS No: 1253740-09-8
    Price: Inquiry(manager@chemfaces.com)
    6-Acetonyldihydrochelerythrine

    Catalog No: CFN98233
    CAS No: 22864-92-2
    Price: Inquiry(manager@chemfaces.com)
    8-Acetonyldihydrosanguinarine

    Catalog No: CFN98608
    CAS No: 37687-34-6
    Price: Inquiry(manager@chemfaces.com)
    8-Acetonyldihydroavicine

    Catalog No: CFN92338
    CAS No: 348098-59-9
    Price: Inquiry(manager@chemfaces.com)
    8-Acetonyldihydronitidine

    Catalog No: CFN92339
    CAS No: 80330-39-8
    Price: Inquiry(manager@chemfaces.com)
    bis[6-(5,6-dihydrochelerythrinyl)]amine

    Catalog No: CFN91015
    CAS No: 165393-48-6
    Price: Inquiry(manager@chemfaces.com)
    Acetylcorynoline

    Catalog No: CFN99749
    CAS No: 18797-80-3
    Price: $168/20mg
    Chelidonine

    Catalog No: CFN90319
    CAS No: 476-32-4
    Price: $158/20mg
    Nat Prod Commun. 2010 Nov;5(11):1751-4.
    Acetylcholinesterase and butyrylcholinesterase inhibitory compounds from Chelidonium majus (Papaveraceae).[Pubmed: 21213973]

    METHODS AND RESULTS:
    The roots and aerial parts of Chelidonium majus L. were extracted with EtOH and fractionated using CHCl3 and EtOH. Repeated column chromatography, preparative TLC and crystallization led to the isolation of five isoquinoline alkaloids, stylopine (3), chelidonine (4), homochelidonine (5), protopine (6), and allocryptopine (7), along with two isolation artifacts 6-Ethoxydihydrosanguinarine (1) and 6-ethoxydihydrochelerythrine (2). All isolated compounds were tested for human blood acetylcholinesterase (HuAChE) and human plasma butyrylcholinesterase (HuBuChE) inhibitory activity.
    CONCLUSIONS:
    The isolation artifacts exhibited the highest activity against HuAChE and HuBuChE with IC50 values of 0.83 +/- 0.04 microM and 4.20 +/- 0.19 microM for 6-ethoxydihydrochelerythrine and 3.25 +/- 0.24 microM and 4.51 +/- 0.31 microM for 6-Ethoxydihydrosanguinarine. The most active of the naturally-occurring alkaloids was chelidonine, which inhibited both HuAChE and HuBuChE in a dose-dependent manner with IC50 values of 26.8 +/- 1.2 microM and 31.9 +/- 1.4 microM, respectively.
    Gancaonin N

    Catalog No: CFN95066
    CAS No: 129145-52-4
    Price: $463/5mg
    Tuberosin

    Catalog No: CFN95107
    CAS No: 41347-45-9
    Price: $218/5mg
    Silychristin B

    Catalog No: CFN95160
    CAS No: 879325-58-3
    Price: $318/5mg
    19-O-beta-D-carboxyglucopyranosyl-12-O-beta-D-glucopyranosyl-11,16-dihydroxyabieta-8,11,13-triene

    Catalog No: CFN95217
    CAS No: 1011714-20-7
    Price: $318/5mg
    Isomargaritene

    Catalog No: CFN95304
    CAS No: 64271-11-0
    Price: $318/10mg
    9,11-Dehydro-beta-boswellic acid

    Catalog No: CFN95335
    CAS No: 471-65-8
    Price: $318/5mg
    (-)-5'-Methoxyisolariciresinol 3alpha-O-beta-glucopyranoside

    Catalog No: CFN95403
    CAS No: 143236-03-7
    Price: $318/5mg
    Crepidiaside B

    Catalog No: CFN95432
    CAS No: 101921-35-1
    Price: $318/10mg
    Ganolucidic acid B

    Catalog No: CFN95513
    CAS No: 98683-75-1
    Price: $413/5mg
    Catechin 7-O-beta-D-glucopyranoside

    Catalog No: CFN95524
    CAS No: 65597-47-9
    Price: $338/20mg