3,4-Di-O-caffeoylquinic acid methyl ester

3,4-Di-O-caffeoylquinic acid methyl ester
Product Name 3,4-Di-O-caffeoylquinic acid methyl ester
CAS No.: 114637-83-1
Catalog No.: CFN90856
Molecular Formula: C26H26O12
Molecular Weight: 530.5 g/mol
Purity: >=98%
Type of Compound: Alkaloids
Physical Desc.: Powder
Targets: HSV
Source: The flowerbud of Lonicera japonica Thunb.
Solvent: DMSO, Pyridine, Methanol, Ethanol, etc.
Price: $388/5mg
3,4-Di-O-caffeoylquinic acid methyl ester shows high efficiency and low toxicity with antivirus activity against RSV; it exhibits cytotoxicity actions against human cervix carcinoma HeLa cells.
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Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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    Functional analyses on antioxidant, anti-inflammatory, and antiproliferative effects of extracts and compounds from Ilex latifolia Thunb., a Chinese bitter tea.[Pubmed: 25118953 ]
    Ilex latifolia Thunb., widely distributed in China, has been used as a functional food and drunk for a long time.
    METHODS AND RESULTS:
    This study was aimed to identify the bioactive constituents with antioxidant, antitumor, and anti-inflammatory properties. I. latifolia was extracted with 95% ethanol and then partitioned into four fractions: petroleum ether fraction, ethyl acetate fraction, n-butanol fraction, and water fraction. Results showed that the ethyl acetate fraction was found to have significant ferric reducing antioxidant power activity, DPPH radical scavenging activity, and oxygen radical absorbance capacity, cytotoxicity against human cervix carcinoma HeLa cells, and inhibitory effect on NO production in macrophage RAW 264.7 cells. Five compounds were isolated from the ethyl acetate fraction, and they were identified as ethyl caffeate (1), ursolic acid (2), chlorogenic acid (3), 3,4-Di-O-caffeoylquinic acid methyl ester (4), and 3,5-di-O-caffeoylquinic acid methyl ester (5), the last two of which were isolated for the first time from I. latifolia. Compounds 4 and 5 exhibited cytotoxicity actions against tumor cell line. Compound 3 showed the strongest anti-inflammatory activity of all the compounds.
    CONCLUSIONS:
    The results obtained in this work might contribute to the understanding of biological activities of I. latifolia and further investigation on its potential application values for food and drug.
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    Study on chemical constituents from Re-Du-Ning Injection (II)[Reference: WebLink]
    To investigate the chemical constituents from Re-Du-Ning Injection (RDN).
    METHODS AND RESULTS:
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    CONCLUSIONS:
    All the isolated compounds are reported from RDN Injection for the first time, and caffeoylquinic acids may be one of antivirus pharmacodynamic material bases of RDN.
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