2-Hydroxy-3-(hydroxymethyl)anthraquinone
2-Hydroxy-3-(hydroxymethyl)anthraquinone exhibits quinone reductase (QR)- inducing activity in Hepa lclc7 cells, with the concentration required to double QR activity of 0.94 microM.
Inquire / Order:
manager@chemfaces.com
Technical Inquiries:
service@chemfaces.com
Tel:
+86-27-84237783
Fax:
+86-27-84254680
Address:
1 Building, No. 83, CheCheng Rd., Wuhan Economic and Technological Development Zone, Wuhan, Hubei 430056, PRC
Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to
24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
STAR Protoc.2024, 5(2):102990.
Appl. Sci. 2021, 11(22),10569
Molecules.2020, 25(15):3353.
Curr Med Sci.2024, 44(2):355-368.
Oncotarget.2015, 6(31):30831-49
Food Hydrocolloids2024, 156:110345
Cardiovasc Toxicol.2021, 21(11):947-963.
Anticancer Res.2024, 44(3):1033-1044.
Int J Mol Sci.2023, 24(18):13713.
Int. Conference on Med. Sci. and Bio.2017, 17973
Related and Featured Products
J Nat Prod. 2007 Dec;70(12):2049-52.
Anthraquinones with quinone reductase-inducing activity and benzophenones from Morinda citrifolia (noni) roots.[Pubmed:
18076142 ]
METHODS AND RESULTS:
Two new benzophenones, morintrifolins A ( 1) and B ( 2), together with 14 known anthraquinones and four other known compounds, were isolated from a chloroform-soluble extract of Morinda citrifolia roots.
CONCLUSIONS:
Of the isolated compounds, four known anthraquinones, namely, 1,2-dihydroxyanthraquinone ( 3), 1,3-dihydroxy-2-methylanthraquinone ( 4), 2-Hydroxy-3-(hydroxymethyl)anthraquinone ( 5), and 1,3,6-trihydroxy-2-methylanthraquinone ( 6), exhibited quinone reductase (QR)- inducing activity in Hepa lclc7 cells, with concentrations required to double QR activity of 12.0, 8.1, 0.94, and 0.56 microM, respectively.
