2-(7-Methoxy-1-naphthyl)ethylamine hydrochloride
Inquire / Order:
manager@chemfaces.com
Technical Inquiries:
service@chemfaces.com
Tel:
+86-27-84237783
Fax:
+86-27-84254680
Address:
1 Building, No. 83, CheCheng Rd., Wuhan Economic and Technological Development Zone, Wuhan, Hubei 430056, PRC
Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to
24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
Environ Toxicol.2023, 23929.
Pharmacol Rep.2017, 69(6):1224-1231
JPC-Journal of Planar Chromatography 2017, 30(2)
Food Science.2023, 4(20):268-282.
Int J Mol Sci.2019, 20(11):E2734
Front Neurosci.2019, 13:1091
Heliyon.2023, 9(6):e16138.
Sci Rep.2019, 9:12132
Int J Mol Sci.2017, 18(12)
Appl. Sci.2020, 10(5),1713.
Related and Featured Products
SI20050030417T on 11 Feb 2005.
Novel process for synthesizing and a novel crystal form of agomelatin as well as pharmaceutical preparations containing these.[Reference:
WebLink]
METHODS AND RESULTS:
Producing agomelatin comprises reacting 7-methoxy-1-tetralone with cyanoacetic acid in presence of organo-ammonium carboxylate catalyst (V), contacting resulting 2-(7-methoxy-3,4-dihydro-1-naphthyl)acetonitrile (VI) with hydrogenation catalyst in presence of allylic compound to give 2-(7-methoxy-1-naphthyl)acetonitrile (VII), hydrogenating (VII) to give 2-(7-Methoxy-1-naphthyl)ethylamine hydrochloride (VIII) and acetylating. Producing agomelatin (N-(2-(7-methoxy-1-naphthyl)ethyl)acetamide) comprises: (i) reacting 7-methoxy-1-tetralone with cyanoacetic acid in the presence of an organoammonium carboxylate catalyst of formula (V) while removing water; (ii) contacting the resulting 2-(7-methoxy-3,4-dihydro-1-naphthyl)acetonitrile (VI) with a hydrogenation catalyst in the presence of an allylic compound to give 2-(7-methoxy-1-naphthyl)acetonitrile (VII); (iii) hydrogenating (VII) in the presence of Raney nickel in ethanol and treating the product with hydrochloric acid to give 2-(7-Methoxy-1-naphthyl)ethylamine hydrochloride (VIII); and (iv) reacting (VIII) successively with.
