Aristolochic acid D

Aristolochic acid D
Product Name Aristolochic acid D
CAS No.: 17413-38-6
Catalog No.: CFN90783
Molecular Formula: C17H11NO8
Molecular Weight: 357.3 g/mol
Purity: >=98%
Type of Compound: Alkaloids
Physical Desc.: Powder
Source: The herbs of Aristolochia debilis Sieb. et Zucc
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Price: $348/10mg
Chinese-herb nephropathy (CHN) is a rapidly progressive renal fibrosis associated with the intake of a Chinese herb (Aristolochia fangchi) containing nephrotoxic and carcinogenic aristolochic acids.
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Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

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The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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    Aristolochic acid D was assigned the molecular formula C17H11NO8 on the basis of elemental analysis and nmr spectroscopy. Methylation with diazomethane yielded the dimethyl derivative 5, and hydrogenation of 5 yielded aristolochic acid-D methyl ether lactam (6), identical with the material of natural origin. The structure of 5 was initially deduced on the basis of spectral evidence, and confirmed by direct comparison with a sample prepared by total synthesis. Spectral arguments are presented which favor structure 4 for Aristolochic acid D.
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