Hot Products

Neridienone B
Catalog No: CFN97057

Neridienone B has significant effects on calcein accumulation. Neridienone exhibits significant leishmanicidal activity against amastigotes of L. mexicana.

Neritaloside
Catalog No: CFN98691

Neritaloside is a cardiac glycoside. Neritaloside exhibits central nervous system depressant activity in mice at a dose of 25 mg/kg.

Nerolidol
Catalog No: CFN98638

Nerolidol, a sesquiterpene used as a food-flavoring agent and currently under testing as a skin penetration enhancer for the transdermal delivery of therapeutic drugs. Nerolidol shows anti-cancer, sedative, antiulcer, antifungal, and antifeeding effects. Nerolidol can inhibit the growth of Leishmania amazonensis, L. braziliensis, and L. chagasi promastigotes and L. amazonensis amastigotes with in vitro 50% inhibitory concentrations of 85, 74, 75, and 67 uM, respectively.

Nerylacetate
Catalog No: CFN93088

Nerylacetate and 1,5-dienes geranyl acetate are catalyzed to the cis-2,5-bis(hydroxymethyl)tetrahydrofurans 3 and 4 by OsO4.

Nevadensin
Catalog No: CFN96492

Nevadensin is an important herb-based constituent inhibiting estragole bioactivation. Nevadensin protects against a methyleugenol-induced marker of hepatocarcinogenicity in male F344 rat. It also exhibits inhibition activity against Mycobacterium tuberculosis, with equal MIC value of 200 microg/mL.

N-Feruloyloctopamine
Catalog No: CFN97707

Niazirin
Catalog No: CFN96998

The Moringa oleifera extract(including niaziridin and Niazirin) can successfully attenuate the development of pulmonary hypertension via direct vasodilatation and a potential increase in antioxidant activity.

Nicotiflorin
Catalog No: CFN99830

Nicotiflorin shows potent antiglycation activity and neuroprotection effects, it has protective effects on cerebral ischemic damage, reducing memory dysfunction, energy metabolism failure and oxidative stress in multi-infarct dementia model rats.

Nicotinamide
Catalog No: CFN99926

Nicotinamide is a form of vitamin B3 that plays essential roles in cell physiology through facilitating NAD+ redox homeostasis and providing NAD+ as a substrate to a class of enzymes that catalyze non-redox reactions. Nicotinamide is an inhibitor of SIRT1, it has insulinotropic action, it can induce differentiation and maturation of human fetal pancreatic islet cells. Nicotinamide may represent a safe treatment for Alzheimer's disease and other tauopathies, and that phosphorylation of tau at Thr231 may regulate tau stability.

Nicotinic acid
Catalog No: CFN91739

Nicotinic acid is an orally active water-soluble B3 vitamin that is an essential nutrient for humans. Nicotinic acid plays a key role in energy metabolism, cell signaling cascades regulating gene expression and apoptosis. Nicotinic acid is also used in the study of cardiovascular diseases. IC50 & Target: Microbial Metabolite; Human Endogenous Metabolite