Hot Products

Corynoxine
Catalog No: CFN90218

Corynoxine is a natural autophagy enhancer, promotes the clearance of Alpha-synuclein via Akt/mTOR pathway, it can significantly inhibit the oxidative stress of PC12 cells.

Corynoxine B
Catalog No: CFN93218

Corynoxine B, a natural autophagy inducer, restores the deficient cytosolic translocation of HMGB1 and autophagy in cells overexpressing SNCA, which may be attributed to its ability to block SNCA-HMGB1 interaction. Corynoxine B exhibits prolongation of the thiopental-induced hypnosis on oral administration in mice.

Corypalmine
Catalog No: CFN97021

Corypalmine (IC50=128.0±10.5 uM) can inhibit prolyl oligopeptidase. (-)-Corypalmine shows inhibition activity against spore germination of some fungi.

Corytuberine
Catalog No: CFN90528

Corytuberine was inhibited only by naloxone and that of bulbocapnine preferentially by yohimbine.

Cosmosiin
Catalog No: CFN98981

Cosmosiin may be beneficial for diabetic complications through their enhanced adiponectin secretion, tyrosine phosphorylation of insulin receptor-β and GLUT4 translocation.

Costunolide
Catalog No: CFN98928

Costunolide has antipyretic, anti-inflammatory, anti-oxidant, anti-carcinogenic and anti-fungal activities, it possesses normo-glycemic and hypolipidemic activity. Costunolide inhibits RANKL-induced osteoclast differentiation by suppressing RANKL-mediated c-Fos transcriptional activity; it inhibits IL-1beta gene expression by blocking the activation of MAPKs and DNA binding of AP-1; it also induces the ROS-mediated mitochondrial permeability transition and resultant cytochrome c release,

Coumarin
Catalog No: CFN99552

Coumarin is an anticoagulant and photoprotective drug; it also has antiulcerogenic activity, which may influence the secretion control mediated by the parasympathetic system. Coumarin is a potent inducer of aflatoxin B1-aldehyde reductase, has chemoprevention of aflatoxin B1 hepatocarcinogenesis.

Coumestrol
Catalog No: CFN96040

Coumestrol is a novel inducer of mitochondrial biogenesis through the activation of Sirt1, it suppresses the accumulation of HIF-1α via suppression of SPHK1 pathway in hypoxic PC-3 cells. Coumestrol can function by inhibiting oncogenic disease, at least in part, through CKII inhibition-mediated cellular senescence. Coumestrol treatment is effective in preventing neuronal loss in all times of administration as well as able to rescue the Na+, K+ -ATPase activity, suggesting its potential benefits for either prevention or therapeutics use against cerebral ischemia in males.

Coumurrayin
Catalog No: CFN99811

Coumurrayin may have anticoagulant activity.

Crassicauline A
Catalog No: CFN90373

Crassicauline A, a diterpenoid alkaloid in Aconitum herbs, is an analgesic drug clinically used in China. Crassicauline A possesses feeding deterrent activity against T. castaneum adults, with the EC(50) value of 1134.5 ppm.