Cedrelone
Catalog No: CFN99368
Cedrelone exhibits antifeedant activity, it has insecticidal activity, it inhibits arval growth of P. saucia, and the molting of the milkweed bug, Oncopeltus fasciatus. Cedrelone and its derivatives exert antimicrobial activities, bromohydroxy cedrelone and Michael adduct show good antifungal activity. Cedrelone is also a very potent inducer of apoptosis, it can cause cell cycle arrest, it shows significant cytotoxicity against cancer cell lines, such as -60, SMMC-7721, A-549, MCF-7 and SW480.
Cedrol
Catalog No: CFN70197
Cedrol shows antifungal activity against the fungus Botrytis cinerea , it has the potential of becoming a new hair growth promoter.
Cedrol has sedative effects, it induces autophagy and apoptotic cell death in A549 non-small cell lung carcinoma cells through the P13K/Akt signaling pathway, the loss of mitochondrial transmembrane potential and the generation of ROS. Cedrol is a potent competitive inhibitor of CYP2B6-mediated bupropion hydroxylase with the inhibition constant (Ki) value of 0.9, μM, it also markedly inhibited CYP3A4-mediated midazolam hydroxylation with a Ki value of 3.4 μM.